摘要
目的研究和探讨超前镇痛在儿童骨科手术中的镇痛效果及安全性。方法将92例骨科手术患儿随机分为两组,治疗组46例,手术前给予非那根和杜冷丁,术中硬膜外注射布比卡因和利多卡因;对照组给予静注氯胺酮和丙泊酚进行麻醉诱导,手术中加注氯胺酮和丙泊酚及琥珀酰胆碱维持麻醉。在麻醉的过程中和手术结束后、4、8、12、24和48 h观察并记录平均动脉压、心率、呼吸频率及血氧饱和度。手术后各时点镇痛程度的评价采用CHIPPS评分法进行评估。记录手术中和手术后不良反应。结果治疗组在手术后8 h平均动脉压、手术结束和手术结束4 h心率、手术结束和手术结束4、8 h呼吸频率及血氧饱和度与本组治疗前和对照组同时间指标相比较,差异有统计学意义(P<0.05)。手术后8、12、24和48 h镇痛程度CHIPPS评分与对照组同期相应指标相比较,差异有统计学意义(P<0.05)。治疗组优44例(95.65%),对照组优37例(80.43%),两组术后镇痛效果优良率比较,差异有统计学意义(P<0.05)。两组术中及术后均无不良反应发生。结论超前镇痛在儿童骨科手术中的镇痛效果满意,安全性好。
【Objective】 To investigate and study effect and safety of advance analgesia in children orthoPaedic surgery.【Methods】92 cases of children with orthoPaedic surgery were randomLy divided into two grouPs,the treatment grouP,46 cases were PreoPeratively given Phenergan and dolantin,intraoPeratively ePidural injection with buPivacain and lidocaine;Control grouP was given anesthesia induction with ketamine and ProPofol,maintenance of anesthesia with ketamine and ProPofol and succinylcholine during the oPeration.In the Process of anesthesia and surgery,after 4 hours,8 hours,12 hours,24 hours and 48 hours,the mean arterial Pressure,heart rate,breathing rate and blood oxygen saturation were observed and recorded.The Pain degree of evaluation was evaluated by CHIPPS scoring method.Record the adverse reactions during and after the oPeration.【Resluts】The treatment grouP in surgery and h mean arterial Pressure,and surgical oPeration over the end and 4 h heart rate,surgical oPeration over and over 4 h,8 h breathing frequency and blood oxygen saturation and the before treatment and control grouP comPared with time index,their difference was statistically significant（P＆lt;0.05）.After surgery and8 h,12 h,24 h,and h analgesia CHIPPS degree evaluation and the corresPonding control indicators in comParison,the difference was statistically significant（P＆lt;0.05）.The treatment grouP oPtimal 44 Patients（95.65%）,and control grouP oPtimal 37 cases（80.43%）,comParing the effect of PostoPerative analgesia of two grouPs,the difference was statistically significant（P ＆lt; 0.05）.there were no adverse reaction occurred in two grouPs intraoPeratively and PostoPeratively.【Conclusion】Analgesic effect of advance analgesia in children orthoPaedic surgery is satisfactory,good safety.
出处
《中国医学工程》
2013年第4期13-14,16,共3页
China Medical Engineering
