摘要
目的通过对慢加急性、慢性肝衰竭患者进行回顾性调查研究，揭示其中医证候的分布特点及其演变规律。方法以回顾性临床研究的方式，对我院165例诊断为慢加急性、慢性肝衰竭患者的病因及中医证候进行分析，为进一步治疗提供临床依据。结果1．慢加急性、慢性肝衰竭的发病年龄以4l～50岁为多；性别以男性为主：而肝硬化是其高危因素；HBV的病毒复制是诱发因素之一；过度劳累、思虑、饮酒是其主发病诱因及加重因素。2．辨证定位多以肝、脾、胆、胃、肾为主；其辨证定性多以血瘀、湿热、热毒、气虚、肝郁为主，主证型为湿热发黄证、气虚瘀黄证、瘀热发黄证、阳虚发黄证。湿热发黄证治疗后总有效率比其他证型高．而气虚瘀黄证和阳虚瘀黄证死亡率高。结论通过对165例患者进行系统的回顾性研究，发现慢加急性、慢性肝衰竭患者具有一定的中医证候分布特点和演变规律。
Objective Through retrospective investigation on 165 patients with acute- on-chronic or chronic liver failure, to reveal the principals of TCM syndrome distribution and its evolution of acute-on-chronic or chronic liver failure. Methods Retrospective study of 165 cases diagnosed with acute-on-chronic or chronic liver failure was conducted to analysis etiol- ogy and TCM syndrome. Results 1. Acute-on-chronic or chronic liver ~hilure mostly attacked males at age 41-50 years; its high risk factor was hepatocirrhosis; one of its induction factors was HBV viral replication; excessive work, worry and alcohol were main factors of induction and exacerbation. 2. TCM differentiation were orientated as problems with liver, spleen, gall, stomach and kidney; the syndromes were normally blood stasis, moistness and heat, toxic heat, qi deficiency and liv- er depression; the main syndrome types were moist heat and yellow, qi deficiency and yellow stasis, stasis of heat and yellow and yang deficiency and yellow. The total effective rate of moist heat and yellow syndrome was higher than the data of other syndrome types. The mortality of qi deficiency and yellow stasis syndrome and yang deficiency and yellow stasis syndrome was higher than the data of other groups. Conclusion Through retrospective investigation on 165 patients with acute-on-chronic or chronic liver failure, it is clear that TCM syndrome distribution and its evolution have certain principles.
出处
《湖南中医药大学学报》
CAS
2013年第1期64-66,共3页
Journal of Hunan University of Chinese Medicine
基金
国家科技重大专项"十一五"课题(2008ZX10005-007)
国家中医药管理局留学回国人员科技择优项目(2005LHR06)
深圳市科技重大项目(JH200505260247A)
关键词
慢加急性肝衰竭
慢性肝衰竭
证候规律
湿热发黄证
气虚瘀黄证
瘀热发黄证
阳虚发黄证
acute-on-chronic liver failure
chronic liver failure
the law of TCM syn- drome
moist heat and yellow syndrome
qi deficiency and yellow stasis syndrome
stasis of heat and yellow syndrome
yang deficiency and yellow syndrome
作者简介
周小舟（1964-），女，湖南湘阴人，博士，主任医师，教授，主要从事中西医结合治疗肝衰竭和原发性肝癌的研究。
