摘要
目的探讨急性心肌梗死患者经皮冠状动脉介入治疗后联用替罗非班对术后支架内血栓形成的影响。方法选取我院2010年1月至2011年1月收治的接受冠状动脉介入治疗的60例急性心肌梗死患者,将其随机分成实验组和对照组,实验组30例,采用冠状动脉介入治疗联用替罗非班的方案;对照组30例,采用直接介入治疗。分别观察两组患者经不同治疗方式后的临床表现。结果实验组患者术后支架内血栓形成例数少于对照组患者(P<0.05),且术后死亡例数较对照组患者减少(P<0.05),差异均具有统计学意义。结论替罗非班对减少急性心肌梗死患者术后支架内血栓的形成具有良好的作用,值得临床上广泛应用。
Objective To explore the effect oftirofiban on stent thrombosis in patients of acute myocardial infarction after percutaneous coronary intervention. Methods Sixty patients of acute myocardial infarction undergoing percuta- neous coronary intervention in our hospital from January 2010 to January 2011 were randomly divided into two groups： the study group and the control group. Patients in the study group （n=30） were treated with percutaneous coronary intervention combined with tirofiban. Patients in the control group （n=30） were treated with percutaneous coronary intervention. The clinical manifestations were observed and compared between the two groups. Results Compared with the con- trol group, the study goup had signigicantly less cases of stent thrombosis and significantly less cases of postoper- ative death （P〈0.05）, with statistically significant differece. Conclusion Tirofiban has a positive impact on reducing the formation of coronary stent thrombosis, which is worth to be widely used in clinical application.
出处
《海南医学》
CAS
2013年第2期174-175,共2页
Hainan Medical Journal
关键词
急性心肌梗死
经皮冠状动脉介入治疗
替罗非班
血栓
Acute myocardial infarction
Percutaneous coronary intervention
Tirofiban, Thrombosis
作者简介
通讯作者：冯军鹏。E-mail：174661797@qq．com.
