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氯吡格雷对糖尿病足浅表溃疡愈合的影响

The efficacy of Clopidogrel Hydrogen Sulfate tablets on superficial ulcer of diabetic foot
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摘要 目的观察氯吡格雷在治疗糖尿病足浅表溃疡中的疗效。方法将本组32例随机分为两组,氯吡格雷组在常规治疗基础上应用氯吡格雷钠75 mg/qd,口服,共4周。结果与治疗前比较,治疗后氯吡格雷组血流变化水平低于对照组,差异具有显著性。糖尿病足溃疡愈合时间显著短于对照组。结论氯吡格雷能改善糖尿病足患者血小板聚集性。 Objective To assess the effect of Clopidogrel Hydrogen Sulfate tablets on superficial ulcer of diabetic foot. Methods Thirty-two patients were evenly divided into control group and Clopidogrel Hydrogen Sulfate tablets group. For Clopidogrel Hydrogen Sulfate tablets group, Clopidogrel Hydrogen Sulfate tablets (75mg, qd, po) was added dai- ly for 4 weeks. Results After treatment one and three minutes and maximum aggregation rates were lower in Copidogre Hydrogen Sulfate group than that in the control (P 〈 0.01 ). The ulcer healing time was shorter in Clopidogrel Hydro- gen Sulfate tablets group (P 〈 0.05). Conclusion Clopidogrel Hydrogen Sulfate tablets can improve platelet aggrega- tion and shorten the healing time of ulcer in patients with diabetic foot.
作者 年秀玲
出处 《中国现代医生》 2013年第2期58-59,共2页 China Modern Doctor
关键词 糖尿病足 溃疡 血小板聚集 氯吡格雷 Diabetic foot Ulcer Platelet aggregation Clopidogrel Hydrogen Sulfate tablets
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