期刊文献+

肺结核患者治疗前后血清降钙素原的变化及其临床意义 被引量:14

Clinical value of serum procalcitonin changes in patients with pulmonary tuberculosis before and after the treatment
在线阅读 下载PDF
导出
摘要 目的探讨肺结核患者治疗前后血清降钙素原的变化及其临床意义。方法应用ELISA方法检测24例肺结核患者治疗前后和18例健康人血清中降钙素原的含量。结果治疗前肺结核患者血清中降钙素原的含量显著高于对照组(P<0.01);治疗后肺结核患者血清中降钙素原的含量显著低于治疗前(P<0.01),且与对照组无统计学差异(P>0.05)。结论检测肺结核患者血清中降钙素原的含量可以用于评价疾病的治疗效果。 Objective To investigate the clinical value of serum procalcitonin (PCT) changes in patients with pulmonary tuberculosis before and after the treatment. Methods The study used ELISA method to detect the PCT levels in 24 patients with pulmonary tuberculosis before and after the treatment and 18 healthy people as the control group. Results The level of PCT in patients with pulmonary tuberculosis before the treatment was obviously higher than that in the controls (P 〈0. 01 ). The content of PCT after the treatment in patients with pulmonary tuberculosis decreased obviously while compared with that before the treatment (P 〈0. 01 ), and had no statistica/ significance while compared with that in the control group. Conclusion It can be helpful for the evaluation of therapeutic efficacy to detect the content of PCT in patients with pulmonary tuberculosis.
出处 《临床肺科杂志》 2013年第1期99-100,共2页 Journal of Clinical Pulmonary Medicine
关键词 肺结核 降钙素原 治疗 pulmonary tuberculosis procalcitonin therapy
  • 相关文献

参考文献6

二级参考文献37

  • 1徐裕海,李桂新,刘谦慧.感染性休克体液复苏治疗后C反应蛋白和降钙素原动态变化的研究[J].大连医科大学学报,2009,31(1):95-97. 被引量:30
  • 2何建平,申昆玲,林影,吴明昌,王咏红,杨学芳,王亚娟,邵芳.前降钙素对新生儿重症感染的诊断价值[J].首都医科大学学报,2005,26(5):545-548. 被引量:22
  • 3王丹,赵美健,徐琦新,孟英韬,宋力.前降钙素在新生儿感染性疾病中的诊断价值[J].天津医药,2007,35(3):192-194. 被引量:10
  • 4中华医学会结核病学分会.中国结核病分类法[J].中华结核和呼吸杂志,1998,21(12):716-716.
  • 5Assicot M,Gendrel D,Carsin H,et al.High serum procalcitonin concentrations in patients with sepsis and infection[J].Lancet,1993,341(8844):515-518.
  • 6Levy MM,Fink MP,Marshall JC,et al.2001 Sccm/ESKM/ACCP/ATS/SIS internationnal sepsis definitions conference[J].Ctit Care Med,2003,31(4):1250-1256.
  • 7Oberhoffer M,Stonauns I,Russwurm S,et al.procalcitonin expres-sion in human peripheral blood mononuclear cells and its moduls-tion by lipopolysaccharides and sepsis-related cytokines in vitro[J].J Lab clin Med,1999,134(1):49-55.
  • 8Dandona P,Nix D,Wilson MF,et al.Procalcitonin increase after endotoxin injection in nomal subjects[J I.J Clin Endocrinol Metab,1994.79(6):1605-1608.
  • 9Monneret G,Pachot A,Laroche B,et al.Procalcitonin and calcitonin gene-related peptide decrease LPS-induced TNF production by hu-man circulating blood cells[J].Cytokine,2000,12(6):762-764.
  • 10Nylen ES,Whang KT,Snider RH Jr,et al.Mortality is incressed by procalcitonin and decreased by an antiserum reactive to procalcito-nin in experimental sepsis[J].Crit Care Med,1998,26(6):1001-1006.

共引文献109

同被引文献117

引证文献14

二级引证文献91

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部