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血尿酸对冠心病患者血管内皮功能的影响分析 被引量:2

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摘要 目的分析血尿酸对冠心病患者血管内皮功能的影响,总结其临床意义。方法选取我院2009年6月—2011年6月72例冠心病患者,设为观察组,再选取同期健康体检者78例,设为对照组,观察比较两组患者的血尿酸水平与血管内皮功能指标。结果观察组的血尿酸水平明显高于对照组,差异有统计学意义(P<0.05);两组肱动脉血流介导的血管舒张功能(FMD)比较,差异有统计学意义(P<0.05);两组硝酸甘油介导的血管舒张功能(FMN)比较,差异有统计学意义(P<0.05)。血尿酸水平与FMD间有明显的相关性(r=-0.38,P<0.05)。结论冠心病患者血尿酸水平显著升高,血管内皮功能显著降低,且血尿酸水平对血管内皮功能有一定影响,能够进一步加快冠心病病情的进展,定期检测冠心病患者的血尿酸水平对指导诊疗,监测疗效及评估预后具有重要的临床意义。
作者 张东俊
出处 《实用心脑肺血管病杂志》 2012年第11期1839-1840,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
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