摘要
目的探讨儿童腹膜后节细胞神经母细胞瘤（GNB）和神经母细胞瘤（NB）的CT影像鉴别特征。方法回顾性分析经手术及病理证实的19例GNB和21例NB患儿的CT表现，对病灶部位、形态、边界、强化方式、强化程度、是否跨越中线、有无钙化、腹部血管受累情况、瘤周及瘤内血管的显示、有无血管瘤栓、周围器官的浸润、淋巴结及远处脏器转移的比较采用χ^2检验或Fisher精确检验比较，对病灶大小的比较采用t检验。结果21例NB组患儿中，病灶位于肾上腺18例、形态规则6例、边缘清楚7例、推移周围大血管7例、包埋血管14例、出现局部浸润及脏器转移10例、淋巴结转移11例、出现瘤周及瘤体内簇状或线状排列的扩张血管影者11例；19例GNB患儿中，出现上述征象者分别为11、12、13、13、6、3、4和4例，差异有统计学意义（χ^2值分别为3．872、4．821、4．912、4．912、4．912、4．607、4．177和4．177，P值均〈0．05）。2组患儿在病灶大小、是否跨越中线、强化方式、强化程度、有无血管瘤栓及钙化上的差异无统计学意义（P〉0．05）。结论NB多位于肾上腺区，可见包埋血管、局部浸润、脏器及淋巴结转移，并显示瘤周及瘤体内簇状或线状排列的扩张血管影；GNB多以形态规则、边缘清楚、推移周围大血管多见。
Objective To compare the CT features of retroperitoneal ganglioneuroblastoma （GNB） and neuroblastoma （ NB ） in children, and summarize the differentiations between them. Methods From November 2007 to November 2011,19 patients with GNB and 21 patients with NB proven pathologically were enrolled in the study. The CT data of GNB and NB were analyzed retrospectively. These tumor parameters in CT included lesion location, size, shape, margin, calcification, across central line, style of contrast enhancement, degree of contrast enhancement, presence of small vessels in or around the tumor arranged in clumps or in line, tumor embolus, adjacent organs invasion or metastasis, lymph node metastasis, and relationship between tumor and surrounding great vessels. These parameters of both groups were compared by X2 and t test. Results In GNB group, 11 patients were located in adrenal gland and 8 patients in the retroperitoneal sympathetic chain; however, in NB group, 18 patients were located in adrenal gland and 3 patients in the retroperitoneal sympathetic chain. The difference were statistical significances in the incidence rate of regular morphology, clear border, vessel encased by tumor, vessels displaced, presence of small vessels in /around the tumor arranged in clumps or in line, adjacent organs invasion or viscera metastasis, lymph node metastasis between NB （ 6/21,7/21,14/21,7/21,11/21,10/21, and 11/21, respectively） and GNB （ 12/19, 13/19,6/19,13/19,4/19,3/19 and 4/19, respectively） （P 〈 0. 05）. However, there was no statistical significance in size, calcification, across central line, contrast enhancement type, contrast enhancement degree between them（ P 〉 0. 05 ）. Conclusions NB are more likely located at adrenal gland and presented a higher incidence rate of presence of small vessels in or around the tumor which arranged in clumps or in line, vessel encased by tumor, adjacent organs invasion or metastasis and lymph node metastasis. Regular morphology, clear border and vessels displaced are more frequently observed in GNB.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2012年第10期907-911,共5页
Chinese Journal of Radiology
作者简介
通信作者：袁新宇，Email：xinyu_y@hotmail．com
