期刊文献+

丙种球蛋白治疗小儿吉兰-巴雷综合征的疗效观察 被引量:2

在线阅读 下载PDF
导出
摘要 目的评价静脉应用丙种球蛋白治疗吉兰-巴雷综合征(GBS)的临床疗效。方法 24例患者随机分成2组,均给予维生素B1、维生素B12、抗感染、营养对症等治疗,对照组静脉滴注人血丙种球蛋白200 mg(/kg.d),治疗组早期静脉滴注人血丙种球蛋白400 mg(/kg.d)。结果治疗组疗效优于对照组(P<0.05),病程缩短,症状改善明显。结论大剂量、早期应用丙种球蛋白对治疗吉兰-巴雷综合征疗效显著,可明显改善患者预后。
出处 《基层医学论坛》 2012年第23期3021-3022,共2页 The Medical Forum
作者简介 张建明,男,本科,主治医师. E-mail:Sx3396185@163.com
  • 相关文献

参考文献2

二级参考文献16

  • 1Dalakas MC.Intravenous immunoglobulin in the treatment of autoimmune neuromuscular disease:present status and practical therapeutic guidelines[J].Muscle Nerve,1999,22:1479-1497.
  • 2Rause I,Blank M,Shoenfeld Y.Anti-DNA and antiphospholipid antibodies in IVIG preparations:in vivo study in nive mice[J].J Clin Immunol,1998,18:52-60.
  • 3Dalakas MC.Blockade of blocking antibodies in Guillain-Barre syndromes:''unblocking''the mystery of action of IVIG[J].Ann Neurol,2002,51:667-669.
  • 4Buchwald B,Ahangari R,Weishaupt A,et al.Intravenous immunoglobulins neutralize blocking antibodies in Guillain-Barre syndrome[J].Ann Neurol,2002,51:673-680.
  • 5Ghetic V,Ward ES.FcRn:the MHC Class I-related receptor that is more than an IgG transporter[J].Immunol Today,1997,18:592-598.
  • 6Campbell DE,Georgion GM,Kemp AS.Pooled human immunoglobulin inhibits IL-4 But Not IFN-γ OR TNF-α secretion following In vitro stimulation oF mononuclear cells with staphylococcal superantigen[J].Cytokine,1999,11:359-365.
  • 7Murata K,Dalakas MC.Expression of the costimulatory molecule BB-1, the ligands CTLA-4 and CD28,and their mRNA in chronic inflammatory demyelinating polyneuropathy[J].Brain,2000,123:1660-1666.
  • 8Basta M,IIIa I,Dalakas MC.Increased in vitro uptake of the complement C3b in the serum of patients with Guillain Barre syndrome, myasthenia gravis and dermatomyositis[J].J Neuroimmunol,1996,71:227-229.
  • 9Rieben AF,Gerritsen AF,Daha MR,et al.IgM enriched IVIG preparations are efficient scavengers of C4 as well as C3 and prevent complement-dependent cytotoxicity of human serum against pig cells[J].Novel Immunosupperessives and Xenotransplantation,1997,25:37
  • 10Samuelsson A,Towers TL,Ravetch JV.Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor[J].Science,2001,291:484-486.

共引文献7

同被引文献7

引证文献2

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部