摘要
目的:系统评价《国家基本药物目录》(2004年版)中的中药注射剂致不良反应/事件(ADR/ADE)类型构成情况,为其合理使用与安全警戒以及风险管理工作提供参考。方法:采用系统性评价及回顾性分析等方法来描述性分析中药注射剂致ADR/ADE类型,并应用帕累托图进行分析。结果与结论:中药注射剂各类ADR/ADE中,皮肤及其附件损害、全身性损害、胃肠系统损害例数分别为2160、1035、446例,构成比分别为46.11%、22.10%、9.52%,累计构成比为77.73%,落在46%～80%区间,为主要类型。临床应重视中药注射剂的ADR/ADE,尤其是上述几类主要的ADR/ADE,促进中药注射剂合理使用。
OBJECTIVE： To evaluate types of ADR/ADE induced by TCM injection in National Essential Drug List （2004 edi- tion） systematically, and to provide reference for rational use and safe suggestions of TCM injections and risk management. METH- ODS： The types of ADR/ADE induced by TCM injection were analyzed descriptively by systematic review and retrospective analy- sis. The statistics of ADR/ADE was analyzed by Pareto chart. RESULTS ＆ CONCLUSION： Of various ADPUADE, case number of lesion of skin and its appendants, systemic damage and gastrointestinal damage were 2 160, 1 035 and 446, and constituent ra- tios were 46.11%, 22.10% and 9.52%, respectively. Accumulative constituent ratio was 77.73%, ranging from 46% -80%. Great importance should be attached to ADR/ADE induced by TCM injection, especially above ADR/ADE, to promote rational use of TCM injection.
出处
《中国药房》
CAS
CSCD
2012年第32期3028-3029,共2页
China Pharmacy
作者简介
姜云达,副主任药师。研究方向:医院中药房管理。电话:021-69695536。E-mail:yundajiang@126.com;通讯作者:杨忠英,主任药师。研究方向:医院药房管理。电话:021-69695536。E-mail:yzy_6322@163.com
