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丹红注射液对肾病综合征患者肾血流动力学及血液黏稠状态的影响研究 被引量:5

Study on the effect for Danhong injection of nephrotic syndrome in patients with renal hemodynamics and blood viscosity state
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摘要 目的探讨丹红注射液对肾病综合征患者肾血流动力学及血液黏稠状态的影响。方法选取2008年7月~2010年12月于某院进行治疗的64例初发原发肾病综合征患者为研究对象,将其随机分为对照组和观察组各32例,对照组采用泼尼松联合双嘧达莫进行治疗,观察组在对照组的基础上加用丹红注射液进行治疗,后将两组患者治疗前及治疗后4周的肾动脉血流动力学及血液流变学指标进行对比。结果治疗后观察组的肾动脉血流动力学及血液流变学指标的改善幅度均大于对照组,治疗后两组上述检测项目比较,P均﹤0.05,差异均有统计学意义。结论丹红注射液在改善肾病综合征患者肾血流动力学及血液黏稠状态方面均发挥着积极的作用,对于改善肾脏血液循环效果明显。 OBJECTIVE To investigate the effect for danhong injection of nephrotic syndrome in patients with renal hemodynamics and blood viscosity state. METHODS 64 cases of primary nephrotic syndrome from July 2008 to December 2010 in our hospital for treatment were chosen as the research object. They were randomly divided into control group of 32 cases and observation group of 32 cases. The control group was taken with splash Nison combined with dipyridamole treatment, and the observation group was treated with Danhong injection on the basis of the control group. The renal hemodynamics and hemorheology indicators of the two groups before treatment and 4 weeks after treatment were compared. RESULTS After treatment, the improvement of renal blood flow mechanics and hemorheology magnitude in the observation group was greater than the control group. The test items of the two groups after treatment were compared (P﹤0.05), and there was significant difference between the two groups. CONCLUSION Danhong injection plays an active role in improving the patients with nephrotic syndrome, renal hemodynamics and blood viscosity state, and has a significant effect of renal blood circulation.
出处 《现代预防医学》 CAS 北大核心 2012年第12期3128-3129,3131,共3页 Modern Preventive Medicine
关键词 丹红注射液 肾病综合征 肾血流动力学 血液黏度 影响 Danhong injection Nephrotic syndrome Renal hemodynamics Blood viscosity
作者简介 李海剑(1977-).男.硕士,主治医师.研究方向:慢性肾衰防治
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