摘要
目的探讨卡介菌多糖核酸联合重组人干扰素α-2b乳膏治疗面部扁平疣的临床疗效。方法 83例面部扁平疣患者,年龄20～43岁,平均32.8岁,男28例,女55例,随机分为2组:治疗组隔日1次肌注卡介菌多糖核酸注射液1ml;每天清洁患处后使用重组干扰素α-2b乳膏,每日涂抹患处4次;对照组给予肌注卡介菌多糖核酸注射液1ml,隔日1次。8周后对疗效进行观察判定。结果治疗组有效率79.55%,对照组有效率56.41%。结论卡介菌多糖核酸联合重组人干扰素α-2b乳膏治疗面部扁平疣的临床疗效显著,治疗过程中无严重不良反应,值得临床推广。
Objective To investigate curative effect of the BCG polysaccharides nucleic acid combined with recombinant human interferon α-2b cream in the treatment of facial flat wart.Methods Eighty-three cases of facial flat wart patients,20~43 years old,average 32.8 years old,male 28,female 55,were randomly divided into 2 groups： treatment group was subjected to intramuscular injection of 1mL BCG polysaccharides nucleic acid once every other day;then skin cleaning,recombinant interferon α-2b cream was applied to the affected area 4 times a day;the control group was given intramuscular injection of 1ml BCG polysaccharides nucleic acid once every other day.The curative effects were observed after 8-week treament.Results The effective rate of treatment group is 79.55%,the effective rate of control group is 56.41%.Conclusion The treatment of the BCG polysaccharides nucleic acid combined with recombinant human interferon α-2b cream gains evident treatment effectiveness for facial flat wart,can be a promising therapeutic alternative.
出处
《四川解剖学杂志》
2012年第1期25-26,共2页
Sichuan Journal of Anatomy
关键词
卡介菌多糖核酸
重组人干扰素Α-2B
扁平疣
BCG polysaccharides nucleic acid
Recombinant human interferon α-2b
Flat wart
