摘要
目的:为新鱼腥草素钠的结构确证提供波谱学依据。方法:通过红外光谱(IR)、一维(1H、13C)和二维(1H-1H COSY、HMQC、HMBC)核磁共振光谱(NMR)、质谱(MS)等波谱法研究新鱼腥草素钠的波谱性质。结果:确认了新鱼腥草素钠IR信号峰;归属了NMR中1H、13C信号的化学位移;详细分析了新鱼腥草素钠MS中主要碎片离子的裂解途径。结论:经波谱学研究确证了新鱼腥草素钠的结构。
OBJECTIVE：To provide the spectral evidence for the structural identification of sodium lauroyl-α-hydroxyethyl sulfonate.METHODS：The spectral properties of sodium lauroyl-α-hydroxyethyl sulfonate were studied through spectroscopic methods including IR,1D and 2D NMR,and MS spectroscopic techniques.RESULTS：In the paper,the assignment of IR signals and 1H,13C chemical shifts had been completed,and the main cleavage pathways of fragment ions in MS spectrum had also been analyzed in detail.CONCLUSION：The structure of sodium lauroyl-α-hydroxyethyl sulfonate is verified by intensive spectral studies.
出处
《中国药房》
CAS
CSCD
2012年第19期1777-1779,共3页
China Pharmacy
关键词
新鱼腥草素钠
结构解析
波谱学
Sodium lauroyl-α-hydroxyethyl sulfonate
Structural elucidation
Spectroscopy
作者简介
兰玉梅,药师。研究方向:医院药学。电话:028-85503059。E-mail:837338355@qq.com;通讯作者:张伶俐,主任药师,硕士研究生导师。研究方向:循证临床药学和药事管理学的研究与实践、循证决策与管理。E-mail:zhlingli@sina.com
