摘要
微小RNA(miRNAs)作为一类内源性非编码小分子RNA,是高等生物生长发育的重要调节因子。miR-21被认定为miRNA转录的主要驱动力,其在人类多种实体肿瘤中高表达,参与细胞增殖、分化、凋亡,且与肿瘤生长、侵袭、转移等密切相关。
miRNAs are endogenous,non-coding small RNAs that play an important role in the growth and development of higher organisms.miR-21 is recognized as the main driving force of miRNA＇s transcription,which has a high-expression in many solid tumors of human and take part in cell proliferation,differentiation and apoptosis,and so that it is closely related to tumors＇ growth,invasion and metastasis.
出处
《大连医科大学学报》
CAS
2012年第2期182-188,共7页
Journal of Dalian Medical University
作者简介
李先承（1970-），北京人，副教授，博士研究生。E—mail：lxc2620@163．com
