摘要
目的了解益阳市中心医院2011年1～11月临床分离获得的主要抗菌药物的耐药情况,为临床合理用药提供可靠依据。方法采用VIEK32细菌鉴定仪及GNS448药敏板进行药敏试验。结果 2011年1～11月我院共分离获得细菌菌株1500株,其中革兰阴性菌(G-)984株(65.58%),革兰阳性菌(G+)516株(34.42%);分离获得的肺炎克雷伯菌和大肠埃希菌、金黄色葡萄球菌分别居前3位。肠杆菌科中的肺炎克雷伯菌和大肠埃希菌产超广谱β-内酰胺酶(ESBL)菌株检出率分别为61.27%和20.04%;分离获得的菌株对美洛培南等碳青霉烯类抗生素耐药率最低,对氟喹诺酮类药物耐药率较高,铜绿假单胞菌和鲍曼不动杆菌对各种受试抗菌药物的耐药率均超过18%。结论我院分离获得的病原菌以院内感染的常见病原菌为主,加强细菌耐药监测对抗菌药物的临床应用和控制细菌耐药性传播具有重要意义。
Objective Understanding of the Central Hospital of Yiyang city in 2011 January to November clinical isolates obtained major antimicrobial drug resistance, and provide a reliable basis for clinical rational drug use. Methods Used VIEK32 bacteria identification instrument and GNS448 susceptibility plate for drug sensitivity test. Results 2011 January - November in our hospital were isolated bacterial strains in 1500 strains, including gram-negative bacteria （G） and 984 strains （65. 58% ）, gram positive bacteria （G＋ ） and 516 strains （34.42%） ; isolated from pneumonia Cray Borrelia bacteria and Escherichia coli, Staphylococcus aureus were ranked in the top 3. Enterobacteriaceae of Cray Borrelia bacteria and Escherichia coli producing extended spectrum beta - lactam enzyme （ESBL） strains were detected respectively by 61.27% and 20.04% ,iso- lated from strains of meropenem and carbapenem antibiotic resistance rate, higher rate of drug resistance to fluoroquinolones, Pseudomonas aeruginosa bacteria and Bauman Acinetobacter on various subjects of antimicrobial drug resistance rate of more than 18%. Conclusion My courtyard isolated pathogens in nosocomial infection pathogen mainly, strengthen the surveillance of bacterial resistance to anfimicrobial drugs in clinical application and control of bacterial resistance to antibiotics is important.
出处
《中国现代药物应用》
2012年第3期7-9,共3页
Chinese Journal of Modern Drug Application
关键词
细菌
耐药性
监测
Bacterium
Resistance
Surveillance
