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阿魏酸、根皮素和水溶性VE的抗氧化协同效应及其配方优化 被引量:9

Synergistic Effect and Formulation Optimization of Three Antioxidant Food Factors
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摘要 采用等效面分析法对抗氧化剂配方阿魏酸、根皮素和水溶性VE清除DPPH自由基能力、还原Fe3+能力及清除ABTS+.能力进行协同性分析,结果表明:随配方中各成分含量不同则呈现出协同、拮抗和相加效应;以归一值(OD值)作为整体效应评价指标并采用响应面优化法(RSM法)进行配方优化,优化模型显示,综合效应最优配方为:阿魏酸34.9%、根皮素35.1%、水溶性VE 30%。 In this work, equivalent surface analysis was used to evaluate the synergistic effect of a new antioxidant formula containing ferulic acid, phloretin and soluble vitamin E on DPPH radical scavenging activity, Fe3+ reducing power and ABTS radical scavenging activity. The results indicated different mixing ratios of the antioxidant factors exhibited a synergistic, antagonistic, or additive effect to some extent. In this study, response surface methodology (RSM) was adopted for optimizing the formulation of the antioxidant factors to achieve the highest OD (overall desirability) value. The optimal formulation consisted of 34.9% ferulic acid, 35.1% phloretin and 30% soluble vitamin E.
出处 《食品科学》 EI CAS CSCD 北大核心 2012年第3期33-38,共6页 Food Science
基金 食品科学与技术国家重点实验室自由探索项目(SKLF-TS-200914)
关键词 阿魏酸 根皮素 水溶性VE 抗氧化 等效面分析 响应面 ferulic acid phloretin soluble vitamin E antioxidant equivalent surface analysis RSM
作者简介 孙玥(1987-),女,硕士,主要从事天然产物开发与研究。E-mail:sunyuc@ncu.edu.cn 通信作者:余燕影(1963-),女,教授,硕士,主要从事天然产物开发与研究。E-mail:yuyanying@ncu.edu·cn
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  • 1PACKER L,CLMAN C.The antioxidant miracle:your complete plantfor total health and healing[M].New York:Wiley,1999:14-28.
  • 2胡益勇,徐晓玉.阿魏酸的化学和药理研究进展[J].中成药,2006,28(2):253-255. 被引量:211
  • 3Alan wild. Russell's soil conditions and plant growth[ M] . Longman,London and New York, 1988.564-607.
  • 4ZHANG Kai,DAS N P.Inhibitory effects of natural plant polyphenolson rat liver glutathione S-transferases[J].Biochem Pharmacol,1994,47(11):2063-2068.
  • 5陆晓宇,曾耀英,叶燕霞,周玉英,慕静静,赵晓慧.根皮素的抗炎和免疫抑制作用(英文)[J].药学学报,2009,44(5):480-485. 被引量:19
  • 6LIU Ruihai.Health benefits of fruit and vegetables are from additive andsynergistic combinations of phytochemicals[J].Am J Chin Nutr,2003,78(3):517S-520S.
  • 7DAI Fang,CHEN Weifeng,ZHOU Bo.Antioxidant synergism of greentea polyphenols withα-tocopherol and L-ascorbic acid in SDS micelles[J].Biochimie,2008,90(10):1499-1505.
  • 8J Baleden, A Mariotti & D Boisgonter. Effect of tillage on soil organic carbon mineralization estimated from 13 C aundance in maize field[J]. Journal of Soil Science. 1990, 41,587 -596.
  • 9Hussain K R Olson and S A Ebelhar. Long- term tillage effects on soil chemical properties and organic matter fractions[ J]. Sci. Soc. Am. J. ,63:1335 - 1341.
  • 10SHROEDER M T,BECKER E M,SKIBSTED L H.Molecular mecha-nism of antioxidant synergism of tocotrienols and carotenoids in palmoil[J].Journal of Agricultural and Food Chemistry,2006,54(9):3445-3453.

二级参考文献47

  • 1王鹏,王玉珠,沈建民.均匀设计及其在药学中的应用[J].沈阳药学院学报,1989,6(4):297-305. 被引量:74
  • 2王剑红,陆彬,胥佩菱,包定元,张自然.肺靶向米托蒽醌明胶微球的研究[J].药学学报,1995,30(7):549-555. 被引量:25
  • 3Miksicek RJ. Interaction of naturally occurring nonsteroidal estrogens with expressed recombinant human estrogen receptor [J]. Steroid Biochem Mol Biol, 1994, 49: 153-160.
  • 4Raja M, Tyagi NK, Kinne RK. Phlorizin recognition in a C-terminal fragment of SGLT1 studied by tryptophan scanning and affinity labeling [J]. Biol Chem, 2003, 278: 491454- 49163.
  • 5Cseb R, Hetzer M, Wolf K, et al. Interaction of phloretin with membranes: on the mode of action of pbloretin at the water- lipid interface [J]. Eur Biophys, 2000, 29: 172-183.
  • 6Auner BG, Valenta C, Hadgraft J. Influence of lipophilic counter-ions in combination with phloretin and 6-ketocholestanol on the skin permeation of 5-aminolevulinic acid [J]. Int J Pharm, 2003, 255: 109-116.
  • 7Shao X, Bain N, He K, et al. Apple polyphenols, phloretin and phloridzin: new trapping agents of reactive dicarbonyl species [J]. Chem Res Toxicol, 2008, 21: 2042-2050.
  • 8Olson ML, Kargacin ME, Ward CA, et al. Effects of phloretin on Ca^2+ handling, the action potential, and ion currents in rat ventricular manocytes [J]. Pharmacol Exp Ther, 2007, 321: 921-929.
  • 9Olson ML, Kargacin ME, Ward CA, et al. Effects of phytoestrogens on sarcoplasmic/endoplasmic reticulum calcium ATPase 2a and Ca^2+ uptake into cardiac sarcoplasmic reticulum [J]. Pharmacol Exp Ther, 2006, 316: 628-635.
  • 10Devi MA, Das NP. In vitro effects of natural plant polyphenols on the proliferation of normal and abnormal human lymphocytes and their secretions of inerleukin-2 [J]. Cancer Lett, 1993, 69: 191-196.

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