摘要
综述了β-石竹烯及其衍生物的活性及合成方法。在活性方面,β-石竹烯作为香料已经被应用于化妆品和食品添加剂中,药理研究表明β-石竹烯具有局麻作用、抗炎作用、驱蚊虫作用、抗焦虑、抗抑郁作用,β-石竹烯醇还应用于镇咳祛痰药物中,石竹烯氧化物具有镇痛和抗炎作用,抗真菌作用,还有细胞毒性等。同时还简单介绍了β-石竹烯及其部分衍生物的合成方法。
The activities and synthesis of β-caryophyllene and its derivatives are summarized by reviewing the related literatures.In activities,β-caryophyllene has been used in cosmetic and food as a fragrance material.The pharmacological studies show that β-caryophyllene has the local anesthetic effect,and the effects of anti-inflammatory,repelling insects and treating general anxiety neurosis and depression.The β-caryophyllene alcohol is also applied in preparing medicament for codein and eliminating phlegm.Caryophyllene oxide has the effects of analgesic and anti-inflammatory,antifungal activities,cytotoxicity,etc.This paper also gives a brief introduction of the synthesis methods of β-caryophyllene and some of its derivatives.
出处
《林产化学与工业》
EI
CAS
CSCD
北大核心
2012年第1期104-110,共7页
Chemistry and Industry of Forest Products
基金
云南省教育厅科学研究基金(08Y0317)
关键词
β-石竹烯
β-石竹烯衍生物
活性
β--caryophyllene β-caryophyllene derivatives
activity
作者简介
刘晓宇(1987-),男,云南大理人,硕士生,主要从事药物化学的研究,E-mail:xp3q@163.com;通讯作者:陈光勇(1974-),男(侗族),贵州剑河人,副教授,硕士生导师,主要从事药物化学的研究,E-mail:chengy997@sina.com
