摘要
目的优选乳香烘制法的最佳炮制工艺。方法以刺激性成分挥发油的总峰面积、峰数目和刺激性试验(兔眼充血与水肿)等4个评价指标,采用正交试验法,对温度、时间、放置厚度、药材直径等4个因素的水平进行优选。结果乳香最佳烘制工艺为A2B3C1D1,即乳香直径0.5 cm,放置1 cm厚,120℃烘制2 h。结论优选出的炮制工艺合理、简单、可行、效率高,可为大规模生产提供参考依据。
Objective In order to select the best baking process of frankincense.Methods Taking the indexes of stimulating components,peak area and number of essential oil and irritant test(hyperemia and hydroncus in rabbit eye),baking temperature,time,thickness,diameter of Frankincense were optimizated by orthogonal design test.Results The best baking technology were A2B3C1D1,diameter of Frankinceuse 0.5 cm,thickness 1 cm,120 ℃baking for 2 h.Conclusion The baking method was reasonable,simple,feasible and high efficiency,it can provide a certain reference for mass-production.
出处
《中国药业》
CAS
2012年第1期36-37,共2页
China Pharmaceuticals
作者简介
作者简介:胡素连(1971-),女,湖南宁乡人,汉族,副主任药师,硕士研究生,主要从事中药制剂开发与研究工作,(电子信箱)741262756@qq.com;
蒋孟良(1954-),男,教授,硕士研究生导师,本文通讯作者,(电子信箱)hhjmL@163.com。