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婴儿痉挛症与促肾上腺皮质激素释放激素假说 被引量：7

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摘要 婴儿痉挛症是一个高度年龄特异性的癫痫综合征，主要特征为特殊的痉挛发作、脑电图呈高峰节律紊乱，常伴智力低下。目前发病机制仍不明确。本文就促肾上腺皮质激素释放激素（corticotropin releasing homwne，CRH）假说作一综述。CRH具有促癫痫作用，增加未成熟脑的兴奋性并在应激下过度表达，这被认为是婴儿痉挛症发病的CRH增高假说。
作者 王雅洁 邹丽萍
机构地区 军医进修学院解放军总医院儿科
出处 《实用医学杂志》 CAS 北大核心 2011年第24期4504-4505,共2页 The Journal of Practical Medicine
关键词 促肾上腺皮质激素释放激素 婴儿痉挛症 假说 癫痫综合征 高峰节律紊乱 发病机制 痉挛发作 智力低下
分类号 R742.1 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献17

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二级参考文献4

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共引文献7

同被引文献70

  • 1郑苏,陈述花,李华,邓劼,陈春红,王晓慧,冯卫星,韩萧迪,张雨佳,李娜,李莫,方方.脑电变化和BASED评分与54例婴儿痉挛症促肾上腺皮质激素疗效的相关性[J].山东大学学报（医学版）,2022,60(9):91-96. 被引量：3
  • 2徐亭亭,乔云飞.通筋透骨汤结合针刺促进痉挛性脑瘫患儿康复效果分析[J].辽宁中医杂志,2022,49(5):119-122. 被引量：4
  • 3anne t.berg samuel f.berkovic martin j.brodie 陆钦池 李静波 孙哲.国际抗癫(痫)联盟经修订的癫(痫)名词及概念:分类和名词委员会报告(上)[J].神经病学与神经康复学杂志,2010,7(3):190-192. 被引量：3
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  • 8Shi XY, Zou LP, Yang G,et al. Prenatal stress exposure hypothesis for infantile spasms [J]. Med Hypotheses, 2012, 78: 735-737.
  • 9Shang NX, Zou LP, Zhao JB, et al. Association between prenatal stress and infantile spasms:a case-control study in China[J]. Pediatr Neurol, 2010, 42(3): 181-186.
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引证文献7

二级引证文献30

实用医学杂志
2011年 第24期

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