摘要
目的探讨血清微量元素铁锌铜及免疫球蛋白与复发性阿弗他溃疡(recurrent aphthous ulcer,RAU)的关系。方法 RAU患者102例作为病例组,选择年龄、性别相匹配的86例健康人群作为对照组,两组分别采集空腹静脉血,用全自动生化分析仪测血清铁、锌、铜含量,用特种蛋白检测仪测血清免疫球蛋白水平,并与正常值比较。结果病例组血清铁的缺乏率14.71%,高于对照组(5.81%),差异有统计学意义(P=0.049);两组间血清锌、血清铜的缺乏率均没有统计学差异(均有P>0.05)。两组间血清免疫球蛋白水平均没有统计学差异。结论 RAU病因复杂,微量元素缺乏、免疫球蛋白异常证据不足,还需进一步做大样本研究。
Objective To study the relationship of Iron,Zinc-Copper,immunogloblin in serum with recurrent aphthous ulcer（RAU）.Methods 102 patients with RAU and 86 healthy controls were recruited.The age and sex were matched in two groups.The concentration of Iron,Zinc,-Copper,immunogloblin were measured in serum by Automatic Biochemistry Analyzer and Special Protein Detector respectively.Results The serum iron of RAU group was more deficient（14.71%） than the control（5.81%）,there was significant difference between two groups（P=0.049）.There was no significant difference of the Zinc,-Copper and immunoglobulin between the two groups（both P0.05）.Conclusions The RAU etiology was complicated.The evidence of minor elements deficiency and immunogloblin abnormality are insufficient.Further study with large sample size are needed.
出处
《中华疾病控制杂志》
CAS
2011年第12期1024-1025,共2页
Chinese Journal of Disease Control & Prevention
基金
哈尔滨医科大学附属第一医院科研基金(2009Y14)
作者简介
闫雅更（1961-），女，黑龙江哈尔滨人，主任医师，硕士。主要研究方向：营养与慢性病。
