摘要
目的探讨克痤隐酮凝胶治疗轻中度寻常痤疮的疗效和安全性。方法根据痤疮的临床诊断和分级标准,将70例轻中度痤疮门诊患者随机分为克痤隐酮凝胶组(治疗组)和维A酸乳膏组(对照组),治疗组每日早晚给予克痤隐酮凝胶外用,对照组每晚给予维A酸乳膏外用,根据皮损数量变化计算消退率判断疗效。结果治疗4周后比较两组疗效和不良反应比较。克痤隐酮凝胶组治疗寻常痤疮有效率91.42%,维A酸乳膏组有效率85.71%,克痤隐酮凝胶组疗效优于维A酸乳膏组,两者疗效比较,差异有统计学意义(P<0.05)。克痤隐酮凝胶组的不良反应发生率为8.57%,A酸乳膏组的不良反应发生率为34.28%,克痤隐酮凝胶组低于A酸乳膏组,两者不良反应发生率比较,差异有统计学意义(P<0.05)。结论克痤隐酮凝胶治疗轻中度痤疮具有疗效显著、副作用小等优点。
Objective To explore the efficacy and safety of moderate acne vulgaris treated with kecuo yintong gel.Methods According to the clinical diagnosis and grading standard of acne,70 cases of moderate acne were divided randomly into a kecuo yintong gel group（treatment group）and a tretinoin cream（control group）in clinic.In treatment group,kecuo yintong gel was used for external application in the morning and evening each day.In control group,tretinoin crease was applied for external administration every evening.According to the changes in skin lesion number,the acne removal rate was calculated and the efficacy was determined.Results In 4 weeks of treatment,the efficacy and adverse events were compared between two groups.The effective rate was 91.42% in treatment group and was 85.71% in control group.The efficacy in treatment group was superior to control group,presenting statistical significance（P0.05）.The morbidity of adverse events was 8.57% in treatment group and was 34.28% in control group,in which,the result in treatment group was lower than that in control group,presenting statistical significance（P0.05）.Conclusion Kecuo yintong gel is characterized as significant efficacy and less side effects in the treatment of moderate acne.
出处
《世界中西医结合杂志》
2011年第11期959-961,共3页
World Journal of Integrated Traditional and Western Medicine
作者简介
通讯作者：蒋兴宁，Email：jun-1971@sohu．com
