摘要
IM To compare the proliferating activity between HBVrelated small hepatocellular carcinoma (HCC) and HCVrelated small HCC.METHODS Sixty liver biopsy specimens from patients with small HCC (≤3cm in diameter) were examined immunohistochemically using antiproliferating cell nuclear antigen monoclonal antibody, of them 30 were HBVrelated HCC and 30 HCVrelated HCC with matched sex and morphologic features.RESULTS The labeling index of proliferating cell nuclear antigen was 79% in HBVrelated HCC and 125% in HCVrelated HCC. There was no statistically significant differences between the two groups (P>005).CONCLUSION In the early phase or small stage of hepatocellular carcinoma, HBVrelated HCC showed similar proliferating activity to that of HCVrelated HCC which suggested that in the early phase, HBVrelated HCC has similar malignancy to HCVrelated HCC.
