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重症监护病房患者中性粒细胞VCS参数检测的临床意义 被引量:2

Clinical significance of neutrophil VCS in patients of ICU
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摘要 目的研究重症监护病房患者感染后中性粒细胞细胞体积(V)、电导率(C)、激光散射(S)参数的变化。方法利用Beckman-Coulter LH750血球仪分别检测98例重症监护病房患者和40例对照组白细胞(WBC)、中性粒细胞(ANC)及其VCS参数:中性粒细胞平均体积(MNV)、中性粒细胞体积分布宽度(NDW)、中性粒细胞平均传导率(MNC)、中性粒细胞平均散射值(MNS),将98例患者根据微生物鉴定结果分为感染组和非感染组。结果感染组患者WBC(12.33±5.39)×109/L、ANC(10.04±5.17)×109/L及其VCS(MNV:157±18,NDW:24.38±4.18,MNC:136±12,MNS:137±11)参数与非感染组〔WBC:(8.71±4.22)×109/L,ANC:(6.79±4.50)×109/L,MNV:151±13,NDW:20.47±3.29,MNC:140±11,MNS:141±12〕、对照组〔WBC:(5.87±3.68)×109/L,ANC:(3.89±2.64)×109/L,MNV:144±8,NDW:18.61±1.39,MNC:144±8,MNS:145±9〕比较差异有统计学意义;非感染组患者WBC、ANC及其MNV、NDW参数与对照组比较差异有学意义;感染组患者经治疗后,细菌再培养阴性组VCS参数MNV(151±15,145±11)、NDW(22.48±3.65,19.31±3.29)与阳性组差异有统计学意义;MNV、NDW参数在感染诊断中要明显优于白细胞、中性粒细胞。结论中性粒细胞VCS参数是反应患者细菌感染的敏感指标。 OBJECTIVE To study the clinical significance of leukocyte VCS of neutrophil patients of ICU.METHODS The WBC,ANC and VCS parameters of neutrophil were examined with Coulter LH 750 hematology analyzer.The parameters examined including mean channel of neutrophil volume(MNV),neutrophil volume distribution width(NDW),mean channel of neutrophil conductivity(MNC)and mean channel of neutrophil scatter(MNS).RESULTS The WBC(12.33±5.39),ANC(10.04±5.17) and VCS parameters(MNV: 157±18,NDW: 24.38±4.18,MNC:136±12,MNS:137±11)of group with bacterial infection were significantly different compared with non-bacterial infection(WBC: 8.71±4.22,ANC: 6.79±4.50,MNV: 151±13,NDW: 20.47±3.29,MNC: 140±11,MNS:141±12) and control group(WBC:5.87±3.68,ANC: 3.89±2.64,MNV: 144±8,NDW:18.61±1.39,MNC:144±8,MNS:145±9).The MNV(151±15,145±11) and NDW(22.48±3.65,19.31±3.29) of patients with bacterial infection were significantly different compared with those of non-bacterial infection after cured.CONCLUSION The VCS parameters can reflect the morphologic change of leukocyte in patients with bacterial infections in ICU.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2011年第19期4054-4056,共3页 Chinese Journal of Nosocomiology
关键词 重症监护病房 中性粒细胞 细菌感染 ICU Neutrophil Bacterial infection
作者简介 通讯作者:陈国千,E—mail:yangyue@sina.com
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  • 1赵丽萍.感染患儿末梢血中性粒细胞百分率和CRP的关系[J].职业与健康,2007,23(10):791-791. 被引量:2
  • 2Richardson-Jones A. An automated hematology instrument fur comprehensive WBC, RBC, and platelet analysis[J]. Am Clin Lab,1990,9:18-22.
  • 3Chaves F, Tierno B, Xu DS. Quantitative determination of neutrophil morphologic changes by Coulter automated hematology analyzer with VCS technology[J]. Mod Pathol,2005, 18:327.
  • 4Chaves F, Tierno B, Bagdasaryan R, et al. Mean neutrophil volume: a new and reliable indicator for acute infection[J]. Mod Pathol, 2005,18 : 261.
  • 5Procop GW, Hartman JS, Sedor F. Laboratory tests in evaluation of acute febrile illness in pediatric emergency room patients. AM J Clin Pathol, 1997, 107 : 114-121.
  • 6Wile M j, Homer LD, Gaehler S, et al. Manual differential cell count help predict bacterial infection;a multivariate analysis. AM J Clin Pathol, 2001, 115: 644-649.
  • 7Manucha V, Rusia U, Sikka M, et al. Utility of haematological parameters and C-reactive protein in the detection of neonatal sepsis. J Paediatr Child Health, 2002, 38: 459-464.
  • 8Ardron M J, Westengard JC, Dutcher TF. Band neutrophil counts are unnecessary for the diagnosis of infection in patients with normal total leukocyte counts. Am J Clin Pathol, 1994, 102: 646-649.
  • 9Wenz B, Gennis P, Canova C, et al. The clinical utility of the leukocyte differential in emergency medicine. Am J Clin Pathol, 1986, 86: 298-303.
  • 10Swaim WR. Laboratory and clinical evaluation of white blood cell differential counts, comparison of the Coulter VCS, Technicon H- 1,and 800-cell manual method. Am J Clin Pathol, 1991, 95: 381-388.

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