摘要
目的探讨胆红素脑病与血清胆红素／血浆白蛋白比值（B／A）的关系。方法对2008年11月至2009年10月本院住院的高胆红素血症患儿进行回顾性总结．分为胆红素脑病组（病例组）与非胆红素脑病组（对照组），对住院期间的血清胆红素高峰值、血浆白蛋白以及B／A等因素之间的关系进行统计学分析。结果共收集到2253例高胆红素血症患儿，其中88例诊断胆红素脑病。病例组B／A为（1．59±0．47），对照组B／A为（0．80±0．28），差异有统计学意义（t=474．537，P=0．000）。B／A比值为0～1．0、1．1～2．0、2．1～3．0时，胆红素脑病发生率分别为0．5％、12．9％、69．2％。结论胆红素脑病的发生与B／A比值有关，B／A越高，发生胆红素脑病的危险性越大。
Objective The relationship between the bilirubin encephalopathy and bilirubin/ albumin （B/A） is discussed. Methods Cases with hyperbilirubinemia in hospital from Dec 2008 to Oct 2009, assigned into bilirubin eneephalopathy group and control group, the relationship among bilirubin peak, albumin and B/A were analyzed retrospectively. Results Of the 2253 babies with hyperbilirubinemia, A total of 88 babies developed bilirubin encephalopathy. The B/A value in bilirubin encephalopathy group was 1.59±0. 47, and control group was 0. 80 ± 0. 28, with significant differences between two groups （t = 474. 537, P = 0. 000）. The incidence of bilirubin encephalopathy at different levels of B/A was different： 0-1.0, 0.5%; 1.1 -2.0, 12.9%; 2.1 -3.0, 69.2%. Conclusion The incidence of bilirubin encephalopathy is significantly associated with the levels of B/A.
出处
《中国新生儿科杂志》
CAS
2011年第5期322-324,共3页
Chinese Journal of Neonatology
作者简介
通讯作者：李贵南，电子信箱：lgn288@yahoo．com．cn
