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夜间无创通气应用于稳定期慢性阻塞性肺病患者的临床效果评价 被引量:6

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摘要 目的系统评价夜间无创正压通气(NNV)应用于稳定期慢性阻塞性肺病(COPD)患者的干预效果。方法通过计算机检索PubMed、OVID、CNKI等数据库,收集符合标准的随机对照试验(RCT),统计学分析采用RevMan5.0软件处理。结果最终纳入12篇RCT,Meta分析结果显示:NNV组与常规组相比,动脉血二氧化碳分压(PCO2)、6 min步行试验(6 MWT)及总睡眠时间的值分别为〔SMD=0.60、P=0.004;SMD=-1.12、P<0.000 01;MD=32.20、P=0.03〕,两组差异有统计学意义;NNV可改善患者的生活质量,在动脉血氧分压(PO2)、肺功能、发病率和死亡率方面差异无统计学意义。结论 NNV可有效降低稳定期COPD患者的PCO2水平,提高运动耐力,改善生活质量,但现有文献资料的质量水平不高,且样本量较小,其效果尚需进一步验证。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2011年第14期2626-2629,共4页 Chinese Journal of Gerontology
基金 天津高等学校科技发展基金计划项目(No.20060121)
作者简介 第一作者:王莹(1984-),女,在渎硕士,主要从事连续护理研究。 通讯作者:张清(1965-),女,副教授,主要从事内科护理研究和慢性阻塞性肺疾病的相关研究。
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参考文献20

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共引文献39

同被引文献75

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二级引证文献65

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