摘要
目的探讨补肾活血疗法对改善不孕症患者促排卵周期子宫内膜容受性的影响。方法将60例子宫内膜生长不良继发不孕患者随机分为研究组[中药+Clomiphene citrate(CC),n=30],对照组[戊酸雌二醇(E2V)+CC,n=30],应用经阴道彩色多普勒超声(TV-CDFI)检测绒毛促性腺激素(HCG)注射日子宫内膜厚度及血流状态。结果两组患者用药后子宫内膜厚度均有改善,但两组之间差异无统计学意义(P>0.05);治疗组子宫内膜阻力指数(RI)和搏动指数(PI)明显低于对照组,差异有统计学意义(P<0.01);子宫内膜穿支血流与对照组比较,差异有统计学意义(P<0.05);治疗组临床妊娠率高于对照组,差异有统计学意义(P<0.05)。结论中药有增加子宫内膜厚度及改善子宫内膜血流的作用,提高子宫内膜容受性,有助于胚胎着床。
Objective To discuss the effect of kidney reinforcing and blood activiating therapy to improve the uterine receptivity in COH cycle of patients with infertility.Methods 60 infertile women with pregnant failures due to poor endometrial development were randomized into two groups：treatment group（traditional Chinese medicine＋Clomiphene citrate（CC）,n=30）,and control group（Estradiol valerate ＋CC,n=30）.Transvaginal color dopper flow imaging（TV-CDFI） was employed to measure the endometrium thickness and bloodstream condition on the day of the human chorionic gonadotropin（HCG） administration.Results The endometrium thickness of both the two groups was improved,but there was no significant difference（P0.05）.The resistance index（RI） and pulsative index（PI） of endometrium in treatment group were obviously lower than that in control group,and there was statistic difference between two groups（P0.01）.The communicating artery of endometrium in treatment group compared with control group showed a significant difference（P0.05）.The pregnancy rate in treatment group was significantly higher than that in control group,showing a significant difference（P0.05）.Conclusion Traditional Chinese medicine with kidney reinforcing and blood activiating has effects of increasing endometrium thickness,improving bloodstream condition and uterine receptivity and it is conducive to embryo implantation.
出处
《中国误诊学杂志》
CAS
2011年第18期4301-4303,共3页
Chinese Journal of Misdiagnostics
关键词
补肾
活血
排卵
子宫内膜/病理生理学
Reinforcing kidney
Activating blood
Ovulation
Endometrium/physiopathology
作者简介
王梅（1967-），女，重庆人，副主任医师，在读硕士。研究方向：妇科内分泌。
