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疏血通对急性缺血性脑卒中的临床疗效研究 被引量:18

Clinical efficacy of Shuxuetong injection on acute ischemic stroke
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摘要 目的评价疏血通在急性缺血性脑卒中的临床疗效。方法选择急性缺血性脑卒中患者196例,按随机数字表法分为治疗组(98例)和对照组(98例),分别在入院时及治疗后2周进行神经功能缺损评分、认知功能障碍评估及临床结局评定,并用经颅多普勒监测治疗前后脑血流量变化。结果治疗组神经功能及临床结局改善及明显改善率明显高于对照组.而恶化病例明显减少。2组治疗后认知功能障碍评分均较治疗前明显改善,差异有统计学意义(P〈0.05),其中治疗组改善更显著。治疗后2组脑血流量较治疗前明显增加,差异有统计学意义(P〈0.05),其中治疗组改善更显著。结论疏血通治疗急性缺血性脑卒中疗效显著.值得推广应用。 Objective To evaluate the therapeutic effect of Shuxuetong injection on acute ischemic stroke. Methods One hundred and ninety-six patients with acute ischemic stroke were randomly divided into Shuxuetong injection treatment group (n=98) and control group (n=98). The neurological deficiency scores, scores of cognitive dysfunction and clinical outcomes were evaluated; and the cerebral blood flow were evaluated by Doppler before treatment and 2 weeks after the therapy. Results The improvement of neurological function and clinical outcomes in the Shuxuetong injection treatment group was more obvious as compared with that in the control group and the improvement rate of patients in the treatment group was higher than that in the controls; Patients in the Shuxuetong injection treatment group enjoyed less worsening than the controls. The cognitive dysfunction 2 weeks after the therapy were significantly improved as compared with those before treatment (P〈0.05); and the cerebral blood flow after the treatment was significantly increased as compared with that before the treatment (P〈0.05); these improvements in the Shuxuetong injection treatment group were much obvious as compared with those in the controls. Conclusion Shuxuetong is effective in treating cerebral ischemic patients.
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2011年第4期402-405,共4页 Chinese Journal of Neuromedicine
关键词 疏血通 缺血性脑卒中 疗效评价 Shuxuetong Cerebral ischemic stroke Therapeutic evaluation
作者简介 通信作者:林香玉,Email:fengkuang—tou@163.com
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