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白癜风与自身免疫研究进展 被引量:7

Research advance in vitiligo and autoimmunity
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摘要 白癜风是一种常见的获得性的以局部或全身色素脱失为特征的皮肤病,人群中的患病率小于2%。通常青少年发病,10~30岁为发病高峰期,各种族均可发生,无明显性别差异。目前发病机制尚不明确,主要有遗传学说,自身免疫学说,氧化应激学说,神经精神学说和病毒学说等[1]。近年来,多数学者认为白癜风是一种多基因遗传的自身免疫性疾病,体液免疫和细胞免疫对黑素细胞的破坏在白癜风形成中起重要作用。现就白癜风与自身免疫相关的研究进展综述如下。
作者 宋文婷 赵广
出处 《中国美容医学》 CAS 2011年第2期327-330,共4页 Chinese Journal of Aesthetic Medicine
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参考文献28

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二级参考文献12

  • 1贺秋豪,高天文,李春英,沈柱,王刚,杨军.白癜风患者血清自身抗体IgG识别人黑素浓集素受体-1B细胞表位的研究[J].中华皮肤科杂志,2005,38(1):29-31. 被引量:5
  • 2田艳丽,李春英,王刚,高天文,卢涛,李淼.In-cellPCR技术扩增白癜风自身抗体基因[J].中华皮肤科杂志,2006,39(1):38-40. 被引量:6
  • 3关翠萍,李永伟,尉晓冬,张迪敏,许爱娥.人酪氨酸酶抗原表位肽的表达、纯化及生物学活性分析[J].中华皮肤科杂志,2007,40(3):139-142. 被引量:1
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