摘要
目的观察静注布托啡诺对剖宫产术中米索前列醇引起的寒战反应的影响。方法选择90例ASAⅠ或Ⅱ级剖宫产手术患者,随机均分为三组:米索前列醇组(Ⅰ组)、布托啡诺+米索前列醇组(Ⅱ组)、对照组(Ⅲ组)。Ⅰ组于胎儿娩出后含服米索前列醇0.4mg同时静注生理盐水5ml;Ⅱ组含服米索前列醇0.4mg同时静注布托啡诺1mg/5ml;Ⅲ组于胎儿娩出后静注生理盐水5ml。观察给药后三组患者寒战发生的情况及镇静评分。结果Ⅰ组寒战反应发生率高于Ⅱ和Ⅲ组(P<0.05或P<0.01),Ⅱ、Ⅲ组Ramsay镇静评分满意率高于Ⅰ组(P<0.01)。结论布托啡诺能有效地预防剖宫产术中米索前列醇引起的寒战,且镇静效果满意。
Objective To assess the effects of intravenous butorphanol on shaking caused by misoprotol used in cesarean section.Methods Ninety ASA Ⅰ or Ⅱ patients undergoing cesarean section were randomly divided into three groups（n=30）：saline group（group Ⅰ）,butorphanol group（group Ⅱ）and control group（group Ⅲ）.Patients in group I were orally given misoprotol 0.4 mg after fetus birth,and intravenously injected with saline 5 ml at the same time.Patients in group Ⅱ were orally given misoprotol 0.4 mg,and intravenously injected with butorphanol 1 mg/5 ml.Patients in group Ⅲ were intravenously injected with saline 5 ml after fetus birth.The development of shaking and sedation degree were observed after the administration.Results Group Ⅰ had a higher shaking incidence than groups Ⅱ and Ⅲ（P〈0.05 or P〈0.01）.The satisfaction rate of sedation score was higher in group Ⅱ than group Ⅰ（P〈0.01）.Conclusion Butorphanol may effectively prevent misoprotol-induced shaking with good sedation effect in cesarean section.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
2011年第1期42-43,共2页
Journal of Clinical Anesthesiology
作者简介
通信作者：阮加萍，Email：Ruanjp668@yahoo．com．cn
