摘要
目的:了解我院药品不良反应(ADR)发生的规律与特点,为临床安全用药提供参考。方法:对我院2009年1月1日～2009年12月20日收集到的252例ADR报告,从报告数量、报告来源、药品种类、给药途径、涉及器官或系统及临床表现等方面进行统计、分析。结果:不良反应报告女性多于男性,60以上患者为敏感人群。静脉滴注是发生ADR的主要给药途径,252例ADR涉及120种药品,其中主要是抗菌药(133例,41个品种)和中药制剂(30例,20个品种),损及皮肤及附件的ADR构成比为46.82%。结论:医院应进一步加强ADR监测与医疗监管工作,促进合理用药。
Objective： To investigate the features of adverse drug reactions （ADR） occurring in our hospital. Method： 252 ADR cases collected in our hospital from January 1, 2009 to December 20, 2009 were statistically analyzed in respect of the number of case reports, source of reports, drug categories, routes of administration, systems involved and the clinical manifestations, et al. Result：The ADRs were more often seen in females than in males. The susceptible population were over 60 years old. The ADRs were mainly caused through intravenous drop infusion. 252 ADR cases reports were involved in 120 kinds of drugs, mainly anti-infective agents（ 133 cases, 41 kinds） and Chinese drug preparations （30 cases, 20 kinds）. Lesions of skin and its appendants accounted for 46.82% of the total ADRs. Conclusion：ADR monitoring and medication intervention should be further strengthened in our hospital to promote rational drug use.
出处
《药物流行病学杂志》
CAS
2010年第12期673-676,共4页
Chinese Journal of Pharmacoepidemiology
关键词
药品不良反应
分析
合理用药
Adverse drug reactions
Analysis
Rational drug use
作者简介
[通讯作者]安薇，Tel：027-83745791，13971225948，E-mail：an-wei0713@yahoo．com.cn
