摘要
血泵的血栓和溶血问题是血泵发展至今一直要研究的重要课题。众多研究成果表明,血泵内血液的复杂流动现象和机械运动产生的高剪切力是造成血栓和溶血问题的主要原因。我们通过与上海儿童医学中心合作,应用计算流体动力学(CFD)计算分析软件FLUENT对该院临床中使用的一种无叶片离心式血泵内部流场特性进行分析研究,结果表明该离心泵内部流场分布较为均匀,剪切力分布基本处于红细胞破碎的临界状态之下,血栓和溶血程度均较轻,有良好的应用前景。
The problem of thrombus and hemolysis in blood pump has always been an important topic to study in the development of the blood pump.Numbers of research results show that it is the complicated flow and the high shear stress of the mechanical movement that result in the thrombus and hemolysis.In this study,with the cooperation of Shanghai Children＇s Medical Center,we have used computational fluid dynamics（CFD） commercial software FLUENT to compute and analyze the flow characteristics in a non-blade centrifugal blood pump.The results figure out that this pump has a reasonable flow distribution and the shear stress distribution is under the critical broken state of red blood cell;meanwhile,there is less thrombus and hemolysis in this pump.So it is in the foreground for clinical use.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2010年第5期1133-1137,共5页
Journal of Biomedical Engineering
关键词
血泵
血栓
溶血
剪切力
FLUENT
Blood pump； Thrombus； Hemolysis； Shear stress； FLUENT；
作者简介
通讯作者。E-mail：y_z_cheng@yahoo．com．cn
