摘要
目的研究阿奇霉素静脉滴注联合布地奈德混悬液雾吸治疗肺炎支原体肺炎(MPP)的疗效观察。方法 2007年1月至2008年3月在吴江市第一人民医院儿科病房住院并确诊为MPP的患儿150例为研究对象,随机分为治疗组、对照组。对照组按传统治疗方案予静脉滴注阿奇霉素抗感染;治疗组在上述综合治疗基础上,加用布地奈德混悬液吸入治疗,观察所有入组患儿临床症状、体征消失及住院时间。结果在缓解发热、咳嗽及住院时间方面,两组差异具有统计学意义(P<0.01);在肺部湿啰音吸收方面治疗组好于对照组,但两组相比差异无统计学意义;肺部X线影像恢复时间两组相比差异无统计学意义(P>0.05)。结论阿奇霉素静滴抗感染联合布地奈德混悬液雾吸,较单用阿奇霉素静滴治疗在缓解临床症状方面具有较显著疗效,且方法简便,患儿依从性好,可在基层医院推广。
Objective Compare the clinic effects and safety of azithromycin infusion,combine with budesonide suspension inhalation to treat Mycoplasma pneumonia with the traditional single infusion of azithromycin.Methods From January 2007 to March 2008,150 in-patient cases diagnosed as MPP were collected in paediatric ward .All cases were randomly divided into treatment group,and the control group.The control group were treated with traditional single infusion of azithromycin ; while the treatment group additionally inhalated budesonide suspension.The time when the clinic symptoms and signs disappear,and the days in hospital of all the cases were observed.Results In alleviating fever,relieving cough,shorten the days in hospital ,there was significant difference between the two groups（P0.01）; the treatment group was better than the control group in absorbing lung′s wet rale ,there was no significant difference（P0.05）; the two groups was no significant difference in lung X-ray recovery time（P0.05）.Conclusion The treatment of infusion Azithromycin combined with budesonide suspension inhalation are better than a single infusion of azithromycin,it is simple,and has good compliance,it worth to promote of grass-roots hospitals.
出处
《临床肺科杂志》
2010年第11期1584-1585,共2页
Journal of Clinical Pulmonary Medicine
