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RICU患者VAP的相关危险因素分析 被引量:4

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摘要 目的探讨呼吸重症监护病房(R ICU)患者呼吸机相关性肺炎(VAP)发病的危险因素,为防治VAP提供科学依据。方法将126例在本院R ICU接受机械通气超过48 h的患者根据是否发生VAP分为VAP组和NVAP组,对与VAP发病可能相关的12个变量进行单因素和多因素Logistic回归分析。结果单因素分析显示,两组机械通气时间、急性生理慢性健康评分Ⅲ(APACHEⅢ)、机械通气前48 h应用抗生素、非感染慢性肺部疾病、留置胃管肠饲营养和重复气管插管与VAP发病密切相关(P<0.05);多因素Logistic回归分析显示,机械通气时间、A-PACHEⅢ评分和机械通气前48 h应用抗生素为VAP的独立危险因素。结论 R ICU中VAP发病与多种临床因素密切相关,临床上应针对相关危险因素进行综合管理与重点监控,以预防和减少VAP发生、提高患者生存率。
作者 周俊荣
出处 《山东医药》 CAS 北大核心 2010年第35期76-77,共2页 Shandong Medical Journal
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