摘要
目的探讨肝细胞肝癌切除后复发的预后相关因素及合理治疗方法。方法１９８３年１月至１９９７年１月２７１例肝癌切除后有１３４例复发，对其一般情况、肿瘤特性及外科措施进行多因素分析，同时比较复发后不同治疗方法的结果。结果复发时间在术后１年内、首次手术时ＡＦＰ＞１０００μｇ／Ｌ、肿瘤直径＞５ｃｍ、门静脉有癌栓、外科切缘为０及术前未行肝动脉插管化疗者等６大因素直接影响复发者的预后，同时发现，复发肿瘤可行再次切除或行肝移植治疗。结论肿瘤特性和外科治疗是直接影响肝癌复发后预后的两大因素，复发后再次肝切除或肝移植可获好的疗效。
Objective In order to demonstrate the associated factors of prognosis and the reasonable treatment in the recurrence of hepatocellular carcinoma patients.Methods From Jan 1983 to Jan 1997,134 cases of recurrence in hepatocellular carcinoma patients were analysized among the following factors(host condition,tumor characteristics and surgical procedures).The different surgical treatments in those patients were simultaneously compared.Results Within 1 year of recurrent time,AFP>1000μg/L in initial operation,tumor size larger than 5cm in diameter,tumor embolization in portal veins,0 of surgical margin and no chemoembolization before the operation were the main factors directly affect the prognosis after recurrence.Repeat hepatectomy and liver transplantation are required to obtain better results.Conclusion Tumor characteristics and surgical treatment were the main factors affect the prognosis after recurrence.Liver transplantation plays an important role in patients who had poor liver function or multi-recurrent tumor sites.
出处
《中国实用外科杂志》
CSCD
北大核心
1999年第5期299-301,共3页
Chinese Journal of Practical Surgery
关键词
肝肿瘤
肝细胞癌
切除术
复发
Hepatocellular carcinoma\ Recurrence\ Treatment
