摘要
目的:探讨青年人原发性肝癌手术切除率低及术后复发率较高的原因。方法:将1985年1月～2000年1月收治的原发性肝癌173例患者分为青年组(≤35岁)83例和中老年组(≥36岁)90例,对其临床资料、手术切除率、术后复发率及生存率等进行比较分析。结果:青年组原发性肝癌手术切除率、术后1年复发率分别为26.51%(22/83)和68.18%(15/22),术后1、3、5年生存率分别为59.09%(13/22)、22.73%(5/22)和9.09%(2/22)。中老年组原发性肝癌手术切除率、术后1年复发率分别为53.33%(48/90)和37.50%(18/48),术后1、3、5年生存率分别为81.25%(39/48)、47.92%(23/48)和39.58%(19/48)。青年组各项生存率指标均较中老年组低(P<0.01)。结论:青年组原发性肝癌具有肿瘤生长迅速、侵袭力强、门静脉癌栓发生率高、多表现为巨块型及弥漫型等特点,导致手术切除率较低及术后复发率较高。
To investigate the causes for low resection rate and high postoperative recurrence rate in the young patients with primary liver cancer （PLC）. Methods： A total of 173 patients with PLC during Jan 1985 to Jan 2000 were allocated to the youth group （≤35y, n=83） and the middle and older age-group （≥36y, n=90）. The clinical data, resection rate, postoperative recurrence rate and survival rate were compared and analyzed. Results： The resection rate and 1-year postoperative recurrence rate were 26, 51%, 53.33% and 68.18%, 37.50%, and the 1-, 3- and 5-year cumulative survival rate were 59.09% and 81.25%, 22.73% and 47.92% and 9.09% and 39.58% in two groups. The prognosis was worse than that in the middle and older age-group （P〈0.01）. Conclusion： Quick growth, strong invasiveness, more portal vein tumor thrombi, massive and diffuse liver cancer are the features of yo.ung patients with PLC. These are also the causes for low resection rate and high recurrence rate in young patients. The early diagnosis helps to promote the resection rate and decrease the rate of postoperative recurrence.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2005年第22期1299-1301,共3页
Chinese Journal of Clinical Oncology
关键词
青年人
原发性肝癌
手术
预后
Young people Primary liver cancer Surgical operation Prognosis
作者简介
通讯作者：褚光平
