摘要
以新橙皮苷和氢气为主要原料,在碱性条件下,用钯-炭作为催化剂合成新橙皮苷二氢查耳酮(NHC)。本实验研究了反应时间、催化剂用量、反应溶剂、氢气压力、反应温度、pH值、搅拌速度等因素对NHC产率的影响。正交实验结果表明制取NHC的最佳反应条件为:反应pH为10,于35℃、2MPa氢气压力、0.8g10%钯炭作为催化剂的条件下,以水作溶剂反应8h,产率达83.5%;在此条件下进行验证实验,所得平均产率为82.7%。
NHC was composed by neohesperidin and hydrogen gas under alkalescent condition with palladium-charcoal as catalyst.The paper studied the yield efficiency of NHC influenced by several factors：reaction time,the dosage of catalyst,reaction solvent,hydrogen pressure,reaction temperature and pH value,stiring speed.Orthogonality experiment indicated the optimal conditions were as the following：pH10,temperature 35℃,2MPa hydrogen pressure,0.8g 10% Pd/C catalyst,water solvent,and reaction time 8h.Under these conditions,the yield efficiency reaches 83.5%,and then through the verification test under these conditions,the average yield is 82.7%.
出处
《中国食品添加剂》
CAS
北大核心
2010年第4期191-195,共5页
China Food Additives
作者简介
杨恒（1987-），男，硕士研究生在读，主要从事食品生物技术方面研究。
