3Thun MJ,Henley SJ,Patrono C,et al. Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues. J. Natl Cancer Inst,2002,94:252-266.
4Etminan M, Gill S, Samii A. Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease : systematic review and meta-analysis of observational studies. BMJ,2003,327 : 128-132.
5Bradbury J. How NSAIDs might prevent Alzheimer's disease. The Lance Neurology ,2004,3:638.
6Antezana DF, Clatterbuck RE, Alkayed N J, et al. High-dose ibuprofen for reduction of striatal infarcts during middle cerebral artery occlusion in rats. J Neurosurg,2003,98:860-866.
7Park EM, Cho BP, Volpe BT, et al. Ibuprofen protects ischemia-induced neuronal injury via up-regulating interleukin-1 receptor antagonist expression. Neuroscience,2005,132:625-631.
8Lefkowith JB. Cyclooxygenase-2 specificity and its clinical implication. Am J Med,1999, 106:S43-S49.
10Bosch-Marce M, Claria J, Titos E, et al. Selective inhibition of cyclooxygenase-2 spares renal function and prostaglandin synthesis in cirrhotic rats with ascites. Gastroenterology, 1999, 116 : 1167-1175.