摘要
以正辛醇-水分配体系模拟中药水煎液中的微量元素在人体肠胃中的分配情况,采用ICP—AES测定灯盏花样品及其水煎液中铝的含量,获取铝的化学形态浓度及分布规律,结果显示:样品中铝的水煮溶出率很低(1.5%~1.7%),总铝及总水溶态铝含量并不存在显著差别,但水煎液中铝的形态存在较大差异,人体不同的胃肠酸碱变化对水煎液中铝的形态分布产生一定影响。这些结果对云南灯盏花的进一步开发利用有一定参考价值。
The system of n - C8H17OH - H2O, which usually used in evaluation of biological function of the organic drugs in the human gastrointestinal system, was adopted to study the distribution of Aluminium in water decoction of Erigeron breviscapus of Yunnan. ICP - AES was used for determination of Aluminium concentration. The extraction rate of Aluminum by water is 1.5% - 1.7%. There are little differences in total amount of Aluminum and total amount of water - soluble Aluminum in different samples. But these data of Kow to evaluate the lipophilicity and bioactivity of the organic medicine revealed that there exist great difference among the samples in speciation of water - soluble aluminum. The changes of gastric and intestinal acidity have some influences on distribution of speciation of water - soluble aluminum. The results are valuable for development and utilization on Erigeron breviscapus of Yunnan.
出处
《云南中医学院学报》
2010年第3期30-32,共3页
Journal of Yunnan University of Traditional Chinese Medicine
关键词
水溶性铝
形态分析
灯盏花
water - soluble aluminium
speciation analysis
erigeron breviscapus
作者简介
马莎(1975-),女,云南人,讲师,主要从事分析化学研究。