摘要
目的研制明尼苏达心功能不全生命质量量表（MLHFQ）中文版，并进行临床试用。方法按照外国语量表汉化为中文版本的标准化程序研制MLHFQ中文版，并对北京市3所综合医院招募的83名住院病人进行测试分析。结果MLHFQ的Cronbach’s α系数在综合分及身体领域、情绪领域均〉0．80；MLHFQ前后2次调查各条目的加权kappa系数在0．48～0．84之间，综合分、身体领域、情绪领域的Spearman相关系数在0．88～0．94之间。MLHFQ与NYHA心功能分级显著相关（P〈0．05），MLHFQ综合分及身体领域、情绪领域与简明健康状况调查问卷（SF-36）的相应维度中高度相关（-0．73～-0．59）。因子分析显示3个因子解释总变异的49．34％。中西医结合治疗前后的MLHFQ得分为：身体领域[（26．15±7．15）分，（17．63±8．50）分]，情绪领域[（8．96±5．73）分，（6．81±5．31）分]，综合得分[（56．38±16．88）分，（39．77±15．69）分]，均差异有显著性（P〈0．01）。结论MLHFQ中文版研制过程和方法规范，信度和效度评价良好，可作为临床测量工具。
Objective To edit Chinese version of the Minnesota living with heart failure questionnaire （MLHFQ） and to estimate its reliability and validity. Methods Translated and edited the Chinese version of MLHFQ according to the standard procedures, and tested 83 inpatients which were recruited from three polyclinics of Beijing district in China. Results Cronbach＇ s alpha consistency was 〉 0.80 for the three MLHFQ scores. Reproducibility ranged from 0.48 to 0.84 for items of weighted kappa coefficient and from 0.88 to 0.94 for three domains of Spearman＇ s correlation coefficient. MLHFQ scores varied significantly with NYHA functional class （P 〈 0. 05 ）, and there were intermediate-to-high correlations with the assumed corresponding SF-36 domains （ - 0.73 to -0.59）. Factor analysis revealed three-factor structure explained 49.34% of the total variance. The MLHFQ scores before and after the treatment combined TCM and western medicine were significant （physical domain （26.15 ±7.15,17.63 ±8.50 ） , emotional domain （ 8.96 ±5.73,6.81 ±5.31 ） , overall score （ 56.38 ±16.88, 39.77 ±15.69 ） all P 〈 0. 01 ）. Conclusions The Chinese version of MLHFQ is translated and edited according to the standard procedures. Its reliability and validity is good, and could be used as a clinical outcome measurement.
出处
《中华行为医学与脑科学杂志》
CAS
CSCD
北大核心
2010年第2期178-181,共4页
Chinese Journal of Behavioral Medicine and Brain Science
基金
国家自然科学基金项目（30873256）
国家中医药管理局中医药科学技术研究专项（04-05LP01）
作者简介
通信作者：朱燕波，Email：yanbo0722@sina．com
