摘要
目的研究乌蕨总黄酮体外抗氧化活性。方法采用分光光度法,测定乌蕨总黄酮对羟自由基、脂质过氧化的清除能力、总还原力和总抗氧化作用,并通过多元线性回归分析,考察了乌蕨总黄酮含量及其体外抗氧化活性的相关性。结果乌蕨总黄酮具有较强的抗氧化性能、自由基清除能力和一定的还原力,可有效抑制脂质过氧化,且抗氧化作用与乌蕨总黄酮含量呈正相关。结论乌蕨总黄酮具有显著的抗氧化活性,黄酮类化合物可能是其抗氧化作用的主要物质基础。
Objective To investigate the antioxidant activity of flavonoids from Stenoloma chusanum （ L. ） Ching in vitro. Methods The radical scavenging, total antioxidant and reducing capacity of hydroxy radicals and lipid peroxides by the total flavonoids from Stenoloma chusanum（ L. ）Ching were detected and analyzed by using spectrophotometry and multiple linear regression analysis. The correlation between contents of total flavonoids and their antioxidant activity in vitro was surveyed. Results The extracts showed strong antioxidant activities, free radical clearance and some reduction ability, by efficiently inhibiting lipid peroxidation in a dose dependent manner. Conclusion The total flavonoids may be the main active component of Stenoloma chusanum （ L. ） Ching which exerting an antioxidative activity.
出处
《医药导报》
CAS
2010年第3期292-294,共3页
Herald of Medicine
关键词
乌蕨
总黄酮
抗氧化
Stenoloma chusanum（ L. ）Ching
Total flavonoids
Antioxidant activity
作者简介
吴晓宁（1974-），女，浙江人，讲师，在读博士，从事天然药物的开发与研究。电话：0571-87692684，E-mail：wxn1974168@126．com。
