摘要
目的了解大学城流感暴发的流行特征,探讨暴发的危险因素,为控制暴发提供科学依据。方法采用现况流行病学调查方法,对该大学城流感暴发的流行特征进行分析;漱口液标本用MDCK细胞进行病毒分离,分离到病毒的标本用血凝抑制试验进行分型鉴定;采用病例对照研究和非条件Logistic回归模型分析此次暴发的危险因素。结果2所学校累计发病人数分别为376例和525例,罹患率分别为1.80%、2.14%。采集的35份现症病人咽漱液中有20份分离出流感病毒,型别鉴定均为H1N1型流感病毒。病人接触史在多因素回归模型中有统计学意义(OR=1.86,1.09-3.18)。结论该事件为由季节性H1N1型流感病毒引起的暴发疫情;病人接触史为此次暴发的危险因素;早期发现、及时隔离治疗病人是控制流感暴发的重要措施。
Objective To explore the epidemiological features and risk factors of influenza outbreak in Higher Education Mega Center and provide scientific evidence for monitoring and adopting effective control measures. Methods Epidemiological survey was conducted to analyze features of the influenza outbreak in two universities. Virus was isolated from collutory samples using MDCK cells and the virus was further identified by hemagglutination inhibition assay. Case control study and nonconditional multiplicity logistic regression model were used to analyze the risk factor of this event. Results Out of 376 and 525 peoples in two schools were infected with influenza, with incidence rates of 1.80% and 2.14%. Influenza virus H1N1 was detected in 20 of 35 collutory samples. History of patient contact had statistical significance in the regression model （OR= 1.86,1.09-3.18）. Conclusion This event in Guangzhou Higher Education Mega Center was diagnosed to be an outbreak of influenza caused by Influenza virus H1N1. History of patient contact was the risk factor of this event. Identifying and isolating the patient in time were the significant measures to control the outbreak of influenza.
出处
《热带医学杂志》
CAS
2010年第1期92-94,共3页
Journal of Tropical Medicine
关键词
流感
暴发
危险因素
influenza
outbreak
risk factor
作者简介
张周斌（1975-），男，本科，主管医师，主要从事现场流行病学工作。
