摘要
目的:研究夏枯草Prunella vulgaris L.果穗中的化学成分。方法:乙醇总提取物经醋酸乙酯萃取,萃取物经反复硅胶柱和SephadexLH-20柱色谱分离和纯化得到单体化合物,根据理化性质和波谱分析数据鉴定化合物的结构。结果:从夏枯草中分离并鉴定了9个化合物,其结构分别为大黄酚(1)、2-羟基-3-甲基蒽醌(2)、汉黄芩素(3)、乌苏酸(4)、β-香树脂醇(5)、α-菠甾醇(6)、α-菠甾酮(7)、β-胡萝卜苷(8)、β-谷甾醇(9)。结论:化合物1～3、7是从该属植物中首次分离得到。
Objective： To study the chemical constituents of Spica Pmnellae. Methods： The ethanol extract of Spica Prunellae was extracted by ethyl acetate. The extract was separated repeatedly by silica gel and Sephadex LH-20 col- tram chromatography. Compounds structures were identified on the basis of physical and chemical properties and spectral data. Results： Nine compounds were isolated from Spica Prunellae, and their structures were identified as ： chrysophanol （ 1 ）, 2-hydroxyl-3 -methyanthraquinone （2）, wogonin （3）, ursolic acid （4）, β-amyrin （5）, α-hessisteml （6）, α-spinasterone （7）, β-daucosteml （8）,β-sitosterol （9） . Conclusion： Compoundsl-3, 7 were isolated from this genus for the first time.
出处
《中国现代中药》
CAS
2010年第1期21-22,46,共3页
Modern Chinese Medicine
关键词
夏枯草
化学成分
Prunella vulgaris
Chemical constituents
作者简介
[通讯作者]刘守金，Tel：（0551）5169036，E-mail：liushjin@hotmail．com
