摘要
目的了解浙江省台州地区妇女感染人乳头瘤病毒(HPV)和年龄分布,以及各亚型与宫颈病变的关系。方法采用聚合酶链反应扩增结合DNA芯片反向点杂交技术,对来浙江省台州市中心医院妇科就诊的2913例患者进行生殖道HPV亚型检测。结果HPV总感染率35.08%,检出前5位依次为HPV16(占7.76%)、HPV11(占7.38%)、HPV52(占6.25%)、HPV33(占4.81%)、HPV58(占4.50%)。结论台州地区妇女生殖道HPV人群感染年龄主要分布在40岁以下,以高危型为主,与宫颈病变的发生密切相关。
Objective The study was conducted to evaluate the prevalence of Human papillomavirus（HPV） infection among women in Taizhou, Zhejiang province, and determine the age distribution and the correlation of different subtypes with cervical lesions. Methods PCR amplification and reverse dot blot DNA chip technology were employed to identify the HPV subtypes for 2913 cases of FIPV infection of the genital tract that visited the central gynecological hospital in Talzhou. Results The overall HPV infection rate was 35.08%, the top five subtypes with the highest rates including HPV16（7.76% ）, HPV11 （7.38%）, HPV52（6.25% ）, HPV33（4.81% ） and HPV58（4.50% ）. Conclusion HPV infections were primarily prevalent in the age group under forty years old, of which high-risk HPV infections were prominent, suggesting high correlation between the infection and the onset of cervical lesions.
出处
《疾病监测》
CAS
2009年第11期849-851,共3页
Disease Surveillance
基金
卫生部科研项目(WKJ2007-3-001)
关键词
人乳头瘤病毒
年龄
宫颈病变
聚合酶链反应
human papillomavirus
age
cervical lesions
poly merase chain reaction
作者简介
王乐见，男，浙江省台州市人，主要从事临床免疫学检测工作
通信作者：李招云，Tel：0576—88526605 Email：LZY8151@163．com
