摘要
目的研究利用Lugol液对食管进行染色对Barrett食管诊断的临床价值。方法选取2007年10月～2008年1月至该院胃镜室行胃镜检查的患者中的114人,病例中包括2005年1月～2007年9月普通内镜检查疑似为Barrett食管而进行回访的患者。随机分为2组,一组接受普通内镜检查,进行常规活检,一组接受Lugol液染色内镜检查,并进行组织活检。结果Lugol液染色内镜组Barrett食管的检出率高于普通内镜组,差异有显著性(P<0.05),Lugol液染色内镜对Barrett食管诊断的敏感性、特异性、阳性预测值、阴性预测值分别为82.1%、79.3%、79.3%和82.1%;普通内镜对Barrett食管诊断的敏感性、特异性、阳性预测值、阴性预测值分别为46.7%、54.8%、26.9%和74.2%。结论Lugol液染色内镜对Barrett食管的病理检出及内镜下诊断均有帮助。
[Objeefive] To investigate clinic value of detecting Barrett＇s esophagus with Lugol＇s staining. [Methods] 114 patients are observed, part of them were suspected with Barrett＇s esophagus. They were divided at random into two groups, one group were stained by Lugol＇ s solution and undergone biopsy. Another group were undergone biopsy by routine endoscopy. [Results] The detection rate of using Lugol＇s staining when endoscopy is higher than routine endoscopy （P 〈0.05）. The sensitivity and specificity, Positive predictive value （PPV）, negative predictive value （NPV） of Lugol＇s staining in diagnosing Barrett＇s esophagus were 82.1%, 79.3%, 79.3%, 82.1%, respectively, while the routine endoscopy were 46.7%, 54.8%, 26.9%, 74.2%, respectively. [Conclusion] The value of Lugol＇s staining in diagnosing Barrett＇s esophagus is superior to routine endoscopy.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2009年第14期2214-2217,共4页
China Journal of Modern Medicine
作者简介
【通信作者】徐雷鸣，男，主任医师，E-mail：leiming．xu@yahoo．com．cn，Tel：020-65790000-6501
