摘要
近年来,西方国家食管贲门交界部腺癌的发病率显著升高。许多研究发现,食管腺癌可由Bar-rett食管(BE)发展而来,BE是食管腺癌最重要的癌前病变,因此BE近年来受到越来越多的重视。BE的诊断主要依赖于内镜及组织病理学检查。最近研究发现,BE的恶变过程中亦存在免疫组织化学改变,这些变化对BE的发生发展有一定提示作用。
In recent years,there has been a rapid increase in esophageal adenocarcinoma. Many studies suggest that esophageal adenocarcinoma may arise from Barrett＇s esophagus（BE）, the premalignant condition. Individuals who with Barrett＇s esophagus are at increased risk of malignant transformation. And it has attracted much research attention in recent years. The diagnosis of patients with Barrett＇s esophagus is still based on endoscopy and systematic biopsy sampling. Immunohistochemical changes associated with development of cancer in Barrett＇s esophagus have attracted much research attention now. And these changes may suggest the development of BE.
出处
《国际消化病杂志》
CAS
2008年第4期299-301,共3页
International Journal of Digestive Diseases
