摘要
为探讨塑料包埋骨髓切片对急性髓性白血病(AML)进行组织学分型的可能性,对74例初诊AML患者的骨髓切片进行Romanowsky型染色的研究。结果4例属增生减退型,70例为增生活跃型。35例为白血性原始细胞的纯一性浸润型,39例为非纯一性浸润型,74例中48例为纤维增生型,26例为非纤维增生型AML。结果表明,在AML的分型中,活检切片对涂片起到补充与纠正作用。
To evaluate the feasibility for a histological classification of acute myeloid leukemia (AML) based on bone marrow biopsy sections . We have studied Romanowskystained , semithin sections of plasticembedded BM biopsies from 74 newly diagnosed AML patients . Four cases were classified as hypoplastic variant of AML , whereas the hyperplastic AML was seen in 70 cases . AML with homogeneous blastic infiltration subtype of the marrow was seen in 35 cases , an inhomogeneous infiltration subtype of marrow with leukemic blasts was seen in 39 patients . 48 cases were classified as AML subtype with marrow fibrosis AML , with marrow nonfibrosis was seen in 26 cases . Our results show that the biopsy section complements and corrects the finding of marrow aspiration in the classification of AML.
关键词
急性
髓性
白血病
骨髓活检
塑料包埋
Acute myeloid leukemia Bone marrow biopsy Plastic embeded histological classification