摘要
目的观察康艾注射液联合TX方案化疗治疗晚期胃癌患者的疗效、毒性反应及对生活质量的影响。方法62例晚期胃癌患者随机分为康艾联合化疗组(治疗组)及单纯化疗组(对照组),其中治疗组32例,对照组30例。评价两组患者近期疗效、毒性反应及生活质量。结果治疗组与对照组近期疗效分别为46.9%和43.3%(P>0.05);治疗组血液及非血液毒性均低于对照组(P<0.05);治疗组生活质量明显改善(P<0.05)。结论康艾注射液联合化疗治疗晚期胃癌,能减轻化疗毒性及改善生活质量。
Objective To evaluate the efficacy, toxicity and effect on quality of life （QOL） in advanced gastric cancer patients treated with Kangai injection combined with TX regimens. Methods Sixty-two patients with advanced gastric cancer were randomly divided into two groups： treatment group（n = 32） received Kangai injection and chemotherapy, and control group （n = 30） only accepted chemotherapy. The response rate, toxicity and QOL were compared between two groups. Results The response rate of treatment and control group was 46. 9% and 43.3% repectively （P〉0. 05）, less toxicity than control group （P〈0. 05）, and the QOL was increased significantly（P〈0. 05）. Conclusion Kangai injection combined with chemotherapy can reduce the toxicity and improve the QOL.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
2009年第4期328-330,共3页
Cancer Research on Prevention and Treatment
关键词
康艾注射液
晚期胃癌
化疗
毒性
生活质量
Kangai injection
Advanced gastric cancer
Chemotherapy
Toxicity
Quality of life
作者简介
张凌（1976～），女，硕士，主治医师，主要从事胃肠肿瘤治疗研究
