摘要
目的调查呼吸道感染患儿的主要病原菌及其对常用抗菌药物的耐药情况。方法采用苛养菌及链球菌鉴定的常规方法对呼吸道感染患儿的咽拭子标本进行分离,培养与鉴定,采用K-B纸片扩散法对分离出的病原菌进行药敏分析。结果300份咽拭子标本中共分离病原菌124株,检出率41.3%,其中苛养菌78株,占病原菌数62.9%;流感嗜血菌对克拉霉素70.0%、复方新诺明60.0%、氨苄西林66.7%耐药率高;肺炎链球菌对四环素96.2%、克林霉素92.3%、复方新诺明92.3%、阿奇霉素(92.3%)耐药率高;酿脓链球菌对四环素100.0%、克林霉素94.45%、阿奇霉素83.33%耐药率高。结论苛养菌和酿脓链球菌是引起儿童呼吸道感染的主要病原菌,治疗时应根据药敏结果合理选用抗菌药物。
OBJECTIVE To investigate pathogenic bacteria isolated from children with respiratory tract infection and bacterial resistance to commonly used antimicrcrobial agents. METHODS Routine methods were used to isolate and identify fastidious bacteria and Streptococcus from children throat swabs. The drug susceptibility tests were performed by Kirby-Bauer method. RESULTS One hundred and twenty four pathogenic bacteria were isolated from 300 samples. The isolation rate was 41.3% and the fastidious bacteria were 78 strains（62.9%）. The resistant rate of Haemophilus influenzae to clarithromycimn, trimethoprim-sulfamethoxazoe （SXT） and ampicllin was 70.0%, 60.0% and 66. 7%, respectively. The resistant rate of Streptococcus pneumoniae to tetracycline, clindamycin, SXT and azithromycin was 96. 2% 92. 3% 92.3% and 92.3%, respectively; the resistant rate of Streptococcus pyogenes to tetracycline, clidamycin and azithromyoin was 100. 00%, 94. 45% and 83. 33%, respectively. CONCLUSIONS Fastidion bacteria and S. pyogenes are the main Pathogenic bacteria in children with respiratory tract infection. The antimicrobial agents should be chosen according to antimicrobial sasceptibility test results.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第8期1013-1014,共2页
Chinese Journal of Nosocomiology
关键词
儿童
呼吸道感染
苛养菌
耐药性
病原菌
Chlildren
Respiratory tract infection
Fastidious bacteria
Drug resistance
Pathogen
