摘要
目的调查儿童呼吸道感染肺炎链球菌对常用抗生素的耐药情况。方法采用ATB细菌鉴定仪及API 20STREP鉴定卡进行细菌学鉴定,用E-test试条检测青霉素G、头孢噻肟和万古霉素的MIC,其他药物的药敏试验采用K-B法。结果 53例肺炎链球菌中,青霉素耐药(MIC≥8μg/ml)的肺炎链球菌占20.7%;红霉素、四环素、复方新诺明和克林霉素的耐药率分别为84.9%,75.4%,73.6%,41.5%;万古霉素、头孢噻肟和利福平的耐药率为0。结论本地区儿童呼吸道分离的肺炎链球菌对常用的抗菌药物有较高的耐药性,应当加强儿童呼吸道苛养菌的分离和耐药性监测,合理使用抗生素,减少耐药菌株的产生。
Objective To investigate the resistance of Streptococcus pneumoniae isolated from children＇s respiratory tract to com- monly used antibiotics. Methods The bacteriology identification were done by ATB bacterium identifying apparatus and API 20 STREP identification card, with E -test method to detect the Antimicrobial Susceptibility for penicillin G, cefotaxime, vanco- mycin, and the others were tested by the K - B method. Results 53 strains of Streptococcus pneumoniae, the resistant rate of penicillin （ MIC^8 I^g/ml） was 20.7%, erythromycin, tetracycline, cotrimoxazole anc~ clindamycin wererespectively 84.9%, 75.4%, 73.6%, 41.5%, Vancomycin, cefotaxime and rifampicin＇s resistant rate is zero. Conclusion The Streptococcus pneumoniae isolated from the region~ childhood respiratory tract to commonly used antimicrobial agents have higher resistance. We should strengthen the monitoring to the separation of the fastidous bacteria and drug resistance in childhood respiratory tract, rationally use of antibiotics, and, reduce the generation of drug - resistant strains.
出处
《中国卫生检验杂志》
北大核心
2014年第17期2570-2571,共2页
Chinese Journal of Health Laboratory Technology
关键词
儿童
呼吸道
肺炎链球菌
耐药性
Children
Respiratory tract
Streptococcus pneumoniae
Resistance
作者简介
胡利春（1979-），女，本科，主管检验技师，主要从事临床细菌学检验工作。
通讯作者：吕火祥，E—mail：la．b_lhx@126．com
