摘要
生存质量(quality of life,QOL)是一个多维的概念,包括生理、心理、社会的满意程度,以及疾病或治疗有关的症状。在肿瘤治疗领域中,QOL评价被广泛应用于临床治疗决策、治疗效果评价、疾病严重程度评定、肿瘤药物效应评价等方面,成为肿瘤治疗研究终点之一。乳腺癌患者由于其发病率高、生存期长、病损部位特殊等原因,QOL往往严重下降。本文综述了常用的乳腺癌患者QOL评价工具,如线性模拟自我评价量表、癌症患者生活功能指标、乳腺癌化疗问卷、癌症生存者生存质量量表、欧洲癌症研究与治疗组织生存质量量表、肿瘤治疗功能评价量表、国际乳腺癌协作组生存质量量表、癌症患者生存质量测定量表等,并分析影响乳腺癌患者QOL的主要因素,这将有助于乳腺癌患者的临床治疗决策和QOL的提高。
Quality of life （QOL） is a multidimensional concept including physical, psychological and social satisfaction, and the symptoms related to disease or treatment. In cancer therapy, QOL assessment is widely used in clinical decision-making, efficacy evaluation, disease status assessment, and evaluation of response to drugs. Because of high incidence, long-term survival and specific localization of breast cancer, patients＇ quality of life is usually seriously decreased. The purpose of this review is to summarize common instruments for quality of life assessment, including linear analogue self-assessment （LASA）, the Functional Living Index Cancer （FLIC）, Breast Cancer Chemotherapy Questionnaire （BCQ）, Quality of Life-Cancer Survivors （QOL-CS）, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire （EORTC QLQ）, Functional Assessment of Cancer Therapy Quality of Life Questionnaire （FACT QLQ）, international breast cancer study group-quality of life （IBCSG-QL）, and Quality of Life Instruments for Cancer Patients （QLICP）. We also analyzed the main factors influencing QOL of breast cancer patients in order to improve clinical decision-making and quality of life.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2009年第7期417-420,共4页
Chinese Journal of Clinical Oncology
关键词
生存质量
治疗
乳腺癌
Quality of life
Treatment
Breast cancer
作者简介
通讯作者：王科明kemingwangcn@126．com
