摘要
将80只15日龄雏鸡随机分为对照组和试验组。试验组雏鸡用传染性支气管炎病毒尿囊液滴鼻染毒,攻毒后1,3,6,9,12d分别测定各组血清中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性与丙二醛(MDA)含量,研究血清中氧自由基在鸡传染性支气管炎发病过程中的动态变化。结果表明:试验组血清SOD,GSH-Px活性自攻毒后明显降低(P<0.05或P<0.01);MDA含量在攻毒后开始上升,且在感染后第6、第9天差异极显著(P<0.01)。提示氧化损伤可能参与调节了传染性支气管炎的发生发展过程。
To investigate the changes of serum oxidative indexes in chickens infected with avian infectious bronchitis virus （ IBV）, 80 chickens of 15-day-old were divided into control and experimental group. Birds in experimental group were infected with IBV by nasal inocu- lation. The superoxide dismutase （SOD） and glutathione peroxidase （GSH-PX） activities and malonaldehyde （MDA） contents were detected in the sera from each group at days 1,3, 6, 9 and 12 after infection, respectively. The results showed that compared with control group, SOD and GSH-Px activities in experiment group significantly decreased after infection （P 〈 0. 05 or P 〈 0.01 ） ; MDA contents increased af- ter infection and were significantly higher than those of control group at days 6 and 9 after infection （ P 〈0. 01 ）. It suggested that oxidative damage might participate in the occurrence and development of avian infectious bronchitis.
出处
《畜牧与兽医》
北大核心
2008年第12期11-14,共4页
Animal Husbandry & Veterinary Medicine
作者简介
王海风（1983-），女，硕士研究生。
通讯作者。
